Company insight High-tech solutions
On a wave of innovating, exciting machinery, Syntegon Technology has developed new solutions for the packaging sector: firstly, an AI inspection system that can reduce false rejection rates on production lines; and, secondly, a Sigpack TTMD cartoner with integrated delta robots, which allows for more flexibility in product feeding. Together, these solutions can increase efficiency and decrease waste for Syntegon’s clients.
yntegon Technology recently installed the first fully validated visual inspection system utilising AI in an automated inspection machine. The installation constitutes a major step in the company’s sustained effort to introduce AI to pharmaceutical visual inspection, thereby exploring largely uncharted territory in the industry. “We are proud to announce this important move, which is the joint result of long-standing visual inspection expertise, solid software and pharmaceutical validation competence, courage to cross boundaries, and an excellent partnership with our customer,” says José Zanardi, responsible for vision inspection development and applications at Syntegon.
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As one of the most challenging stages in the pharmaceutical manufacturing process, inspection requires ever-more sophisticated visual systems to process increasingly complex products. “Especially for high-cost pharmaceuticals, every single false reject is one too many,” Zanardi continues. AI applications have the potential to further increase detection rates and decrease the number of false rejects in difficult products, such as highly viscous parenteral solutions with air bubbles, which are sometimes hard to differentiate from harmful particles. AI utilises deep learning algorithms that are capable of accurately identifying recurring patterns and deviations. “A growing number of deep learning vision applications are already on the market,” Zanardi explains. “Our task was to adapt those applications for pharmaceutical purposes, which essentially also includes validation. In fact, thanks to thorough in-house software and visual inspection expertise, Syntegon was able to develop a solution
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that only requires moderate modifications to the already existing vision systems.” The company leads the field with over 40 years of experience in the development and manufacture of visual inspection machines, covering a wide array of manual, semi-automated and fully automated solutions for all liquid pharmaceuticals and container types.
First successful installation After starting with the AI development in 2017 and performing a large number of tests, Syntegon recently installed its first AI-equipped visual inspection system in a fully automated and validated machine in a customer’s production line. Amgen, one of the world’s leading biotechnology companies, uses the system to reliably distinguish air bubbles at the syringe’s rubber stopper from foreign particles, where conventional vision technology often mistakenly identifies safe products containing bubbles as defective. “This challenging project required a lot of dedication and expertise,” says Manuel Soto, principal process development engineer at Amgen. “In cooperation with Syntegon, we have implemented the world-first syringe inspection machine with AI, [which now] underlines our market position, both in biotechnology production and in technology.” In this customer project, Syntegon’s AI-based vision system was able to increase the particle detection rate by 70%, while reducing the false detection rate by 60% (average values in a particular inspection station). “We are very happy that our new technology is able to contribute to higher safety and production efficiency of injectable drugs,” Zanardi says. Backed by this success, Syntegon is set to implement AI in further inspection machines for different products and container types,
Syntegon has more than 40 years of experience in the development and manufacture of automated visual inspection machines for all liquid pharmaceuticals and container types.
thus contributing to the production of safe and reliable pharmaceutical products worldwide.
Delta force
Sytegon has also recently added a new Sigpack TTMD cartoner with integrated delta robots to its portfolio. Syntegon has expanded its secondary packaging portfolio with a machine for even more flexibility: the Sigpack TTMD combines core technologies of the TTM platform with one or more seamlessly integrated delta robot cells. The robotic solution’s camera-based
Packaging & Converting Intelligence /
www.pci-mag.com
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