CHROMATOGRAPHY 25
emulation technology
Jade C. Byrd explores the instrumentation that is allowing scientifi c organisations to continue historical work while adopting the newest technology
L
iquid chromatography (LC) has long been used to ensure the quality and safety of food, medicine
and commercial products by allowing scientists to determine the identity and quantity of components within a sample. Considerable advances have been made by manufacturers of LC systems to provide higher-performing instruments to record these types of measurements. Scientists using this technique have
long struggled with one eff ect of improved instrumentation: methodologies using earlier-generation hardware produce diff erent results when run on newer or diff erent instrument hardware. One example is experiments performed
by pharmaceutical companies: scientifi c methods are created during the drug development process for quality and stability and these methods must be run worldwide for many years (often 10-20) after the drug is commercially available. Pharmaceutical laboratories are interested in adopting newer technology for both economic and environmental reasons, yet are unable to do so because obtaining diff erent results than those observed previously is not acceptable. T e result is that ageing instrumentation must be kept in use, sometimes after its serviceable lifetime has been reached, and that each laboratory must invest in many types of instruments, leading to more laboratory expense and waste. Agilent Technologies has developed a solution to this fundamental problem.
INTELLIGENT SYSTEM
The Agilent Infi nity II LC system
www.scientistlive.com
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