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New tabletop microscopes with enhanced usability
Hitachi High-Tech Corporation has globally launched the TM4000PlusIII and TM4000III, their latest tabletop microscopes designed for enhanced usability and automation. These compact microscopes are well-suited for research and development, quality control in manufacturing, and educational purposes due to their ease of installation and operation.
The TM4000PlusIII stands out with its automation support, allowing users to create and save recipes for tasks such as stage positioning and magnification adjustments, which can then be executed automatically. This feature is particularly beneficial for users with limited expertise, enabling them to handle large sample observations with consistency and efficiency. Additionally, the microscope includes a high-current mode, which accelerates operations like particle analysis by increasing the observation signal, thereby reducing overall measurement time.
Both models also feature a tungsten filament monitoring system, which graphically reports the filament’s condition. This allows users to anticipate maintenance needs and prevent interruptions during observations, ensuring consistent operation. The TM Series microscopes are also equipped with low-vacuum and high-sensitivity backscattered electron detectors, eliminating the need for complex sample pretreatment, making them ideal for educational settings.
As digital skills become increasingly important in education, the TM4000PlusIII offers an opportunity for users to learn programming concepts through its automation features, making it a valuable tool in classrooms.
Hitachi High-Tech aims to ship 6,000 units of the TM Series globally, supporting manufacturing worldwide while continuing to innovate in measurement and inspection technologies to improve quality of life and address environmental and societal challenges.
More information online:
ilmt.co/PL/Okyq 63248pr@reply-direct.com
Novel nuclear stains for microscopy and flow cytometry Nuclear Stains lineup, providing researchers with unprecedented
Biotium, a leader in fluorescent dyes for life science research, has expanded its NucSpot®
specificity and flexibility for nuclear counterstaining. NucSpot® Nuclear Stains
are membrane-impermeant dyes that selectively target the nucleus with minimal fluorescence until binding to DNA, allowing for convenient no-wash nuclear staining.
This innovative approach distinguishes NucSpot® stains, such as propidium iodide (PI), TO-PRO®
, and TOTO®
from traditional nuclear , by achieving
nuclear specificity in fixed and permeabilised cells without the need for RNase treatment.
Now featuring nine colours across the fluorescence spectrum from green to near-infrared (near-IR), NucSpot® flexibility for multicolour panel design, compatible with channels such as FITC, Cy®
3, PE, Texas Red® , Cy® 5, APC, Cy®
Nuclear Stains offer enhanced 5.5, and Cy®
7. Many
of these stains are non-toxic, suitable for live cell cycle profiling by flow cytometry, and can be used in live cultures for multi-day imaging, providing versatility for a wide range of microscopy and flow cytometry applications.
Dr Lori Roberts, Director of Bioscience at Biotium, remarked: “The expanded NucSpot® lineup offers significant advancements in nuclear
counterstaining by broadening colour options and improving photostability over existing cyanine-based stains, without requiring RNase treatment. This expansion reflects our commitment to innovative, user-friendly tools for cell biology research.”
Biotium’s rigorous in-house testing ensures the reliability and consistency of NucSpot® research applications.
More information online:
ilmt.co/PL/9yz1 63251pr@reply-direct.com Nuclear Stains, making them ideal for advanced
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