Laboratory Products 39 Versatile Pipettes Selected for Prestigious International Competition


Students of Technische Universität Braunschweig, Germany, used Integra Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition. The pipettes helped the team to speed up liquid handling and increase pipetting accuracy, giving the students a competitive edge over their peers.


The iGEM Foundation is an independent, non-profi t organisation dedicated to the advancement of all areas of synthetic biology. It runs an annual international competition where multidisciplinary teams of university students design, build and test their own unique research projects from start to fi nish. The group at Technische Universität Braunschweig (TU_BS) developed a self-amplifying detection system for the competition, which can be used to identify small amounts of tumour marker antigens in blood samples. This novel tool has the potential to contribute to the early diagnosis and treatment of many cancers, improving patient outcomes and survival rates in the long term.


Benjamin Harder, a student at TU_BS, explained: “We were the fi rst iGEM team at our university for some time so, until recently, we had only a few outdated pipettes available to us. We therefore decided to upgrade to I Integra’s VIAFLO electronic pipettes and EVOLVE manual pipettes. They are well suited to our applications, as they allow us to rapidly adjust the dispensing volume on the fl y, making our liquid handling steps faster and more effi cient than before, while simultaneously minimising manual errors and reagent wastage. This noticeably improved the accuracy and reproducibility of our results, giving us greater confi dence in our fi ndings.”


“Every day working on our project in the lab was different and unpredictable, but I Integra’s products greatly helped us to deal with some of the surprises and


challenges we came across as we got closer to the fi nal of the exciting competition,” Benjamin concluded. All teams presented their cutting-edge projects during the iGEM Grand Jamboree in Paris, France, from the 26th to the 28th of October 2022, with prize winners being announced on the fi nal day. TU_BS was awarded a silver medal for their innovative project, a much-deserved reward for the group’s months of hard work.


More information online: ilmt.co/PL/Z4v9 and ilmt.co/PL/QqGX 59583pr@reply-direct.com


Entry-level Laboratory Sample Inventory Management Software


Highly Characterised, High Purity Exosome Standards


Life science specialists, AMSBIO, offer an extensive range of highly characterised, high purity exosomes for use as control standards in applications including marker assessment, immunocapture performance evaluation, exosome quantifi cation, OMICS analysis, fl ow cytometry and electron microscopy.


Exosomes or extracellular vesicles (EV) are small endosome derived lipid nanoparticles (50- 300nm in diameter), actively secreted by exocytosis in most living cells. Exosomes have been shown to have pleiotropic physiological and pathological functions and play signifi cant roles in diverse conditions such as cancer, infectious and neurodegenerative diseases.


Benefi ting from an exceptionally large cell bank built up over several decades, AMSBIO is in a unique position to offer researchers an unmatched range of exosomes from a wide variety of biological sources, including cell culture supernatant, human plasma, serum, and urine. All exosomes supplied by AMSBIO are supplied lyophilised meaning they are easy to ship, store for up to 36 months (+4° to 8°C) and reconstitute.


Samples is a sample management tool, designed by Ziath, for laboratories tasked with keeping smaller inventories of stored samples well organised.


This powerful, yet easy-to-use software suite includes a host of features designed to streamline your sample storage workflows and makes adding and searching sample information quick and simple.


Highly intuitive data import tools allow rapid integration with existing sample databases, while its range of sample entry options and fully editable set-up parameters means the system can be optimised for your laboratory or storage facility.


Samples software includes facility for customisable tracking tags and sample types allowing you to associate fully searchable data with your samples. Creating an unlimited number of tracking tags enables laboratories to precisely describe their samples using a variety of descriptor formats including free text, quantities, dates and even links to documents such as safety or regulatory datasheets.


Laboratories using samples software can simply switch between viewing graphical displays of container layouts or a list of all containers and samples,


Designed to save you time, Samples software allows you to save frequently used searches and customise them for future use. An archive function provides access to historical data, even when a container has been permanently removed from storage,


More information online: ilmt.co/PL/zOAk 58950pr@reply-direct.com


Smaller diameter exosomes are supplied highly purifi ed using a combination of tangential fl ow fi ltration (TFF) and size exclusion chromatography (SEC). Exosomes larger than 150 nm diameter are purifi ed using tangential fl ow fi ltration (TFF). All AMSBIO isolated exosome standards are then quantifi ed and validated for overall protein content, size distribution, concentration, and specifi c marker expression by Nanoparticles Tracking Analysis. This unique combination of high purity and comprehensive marker characterisation delivers exceptionally reliable research results. To track the distribution and movement of specifi c exosome standards, AMSBIO also offers fl uorescent labelling.


For further information on highly characterised, high purity exosome standards, and custom exosome services, please contact AMSBIO. More information online: ilmt.co/PL/4EYB


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