6 Award Winning Manual Press
Specac’s Manual Hydraulic Presses are available in 15 and 25 ton load configurations for a wide variety of laboratory pressing applications. It is well suited to the manufacture of KBr pellets for FTIR spectroscopy as well as sample pellets and targets for other spectroscopic techniques such as XRF. It is also suitable for analysis of polymers and thin films when used with the heated Platens and Constant Thickness Film Makers manufactured by Specac.
Specac know that their press has been used in diverse applications such as cocoa powder analysis and brake pads.
A Doctor at the the University of Ghana, has been analysing unsweetened natural cocoa powder (UNCP) for its potential in amplifying the anti-malarial High Dose Artemether/ Lumefantrine-Induced drug on the liver. Cocoa powder contains antioxidant polyphenols called avonols, which are reported to have liver-protective properties. Using Energy-Dispersive X-Ray Fluorescence (EDXRF), unsweetened natural cocoa powder was analysed before being supplied orally to thirty male guinea pigs under various dosages of the drugs. The findings suggested that the cocoa powder increased nitric oxide levels, however, a higher level of copper was observed, suggesting a detrimental effect of high daily UNCP consumption.
Detecting carcegonics in brake pads by research at Lund University. A 15 ton manual press was used to investigate whether asbestos was found in dust particles from car vehicle brake pads. Brake pads were removed from a selection of vehicles and ground with a 100g hammer (coated with 20 layers of paper to avoid direct contact). An agate mill was then used to homogenise the samples and the filtered pieces were washed and then sieved from water.
The particulate form of this substance has been described as posing a significant cancer risk if consumed, when released through friction (i.e. applying brakes). EDXRF analysis was used to determine the composition of all samples. Findings showed that a significant amount of the dust was determined as inhalable and they also found other toxic metals in the pads and dust, however no asbestos fibres were found in dust which was a relief in this experiment.
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New Triple Quadrupole MS Combines World-class Sensitivity and Ultra-high Detection Speed
Shimadzu has released the LCMS-8060NX triple quadrupole mass spectrometer. Together with world-class sensitivity and detection speeds, this flagship LC-MS system offers further improvements in ease-of-use and robustness. It offers greater operating efficiency to pharmaceutical companies needing to shorten drug discovery periods or reduce costs, clinical firms that handle complex biological samples, and entities in food science involved in investigating residual pesticides among others. The LCMS-8060NX enhances method development and routine analysis.
The LCMS-8060NX offers among the highest sensitivity and detection speeds in the world and includes internal mechanical improvements to promote sample ionisation. This enables high-sensitivity analysis even for compounds that are difficult to ionise.
The newly introduced IonFocus unit reduces instrument contamination by guiding ions to the interior more efficiently and removing unwanted components, which helps to prevent decreases in detection accuracy or sensitivity. In addition, more robust components are used in ion-focusing, enabling more reliable analysis. The LCMS-8060NX therefore offers both higher sensitivity analysis and lower downtime.
The system includes several ‘Analytical Intelligence’ functions to maximise analysis throughput and improve the operational efficiency and productivity of the entire workflow, from preparations for analysis through to data processing. For example, the LCMS-8060NX includes a new ionisation unit that is capable of high-sensitivity analysis without the need for complicated adjustments and enables more efficient method development, as well as functions to start up or shut down analytical instruments automatically in combination with a Shimadzu Nexera LC system.
Shimadzu’s powerful LC-MS range from single to triple quadrupole systems enables more compounds to be screened in less runs while increasing sensitivity and data quality. Many accessories, software, data banks and method packages complement the systems. Depending on the need for sensitivity in the lab, one model always fits, bringing robustness while keeping the flexibility to upgrade at a later stage as soon as requirements change.
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Next-Generation Benchtop X-Ray Elemental Analyser The next-generation benchtop Energy Dispersive X-Ray Fluorescence (EDXRF) spectrometer S2 PUMATM Series 2 from Bruker is equipped with HighSenseTM
Watch the recorded webinar:
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technology
for increases in throughput by about a factor of 3x. Bruker’s software SPECTRA.ELEMENTSTM comes with enhanced features and faster algorithms, leading to ~40% shorter evaluation times. The S2 PUMA Series 2 supports elemental analysis applications from cement, steel, mining and petrochemical, to food analysis and pharma QC. The new mapping stage also extends its applications into semiconductors and coatings, where spatial resolution is required.
Extended Capability and Power for High-Resolution Mass Spectrometers Announced
Waters Corporation has announced a new fragmentation technique and an imaging option for its high-resolution mass spectrometers giving research scientists working across a broad range of end markets including biomedical, biopharmaceutical and food research, greater experimental freedom to explore the intricacies of peptides, proteins, and protein complexes.
“This is a time for science to step up and show what it can do for humanity,” said James Langridge, PhD, Senior Director, Advanced Mass Spectrometry, Waters Corporation. “Understanding the biology of disease and discovering new treatments requires us to continue innovating new and powerful capabilities for mass spectrometry so that scientists can accurately and confidently answer their scientific questions.”
For its high-performance SELECT SERIES™ Cyclic™ IMS System, Waters will offer scientists the ability to probe the structure of proteins, peptides, glycans and other biomolecules with Electron Capture Dissociation (ECD), a fragmentation technique made available through a partnership with e-MSion, Inc.
ECD combined with ion mobility mass spectrometry and Collision Induced Dissociation (CID) available with the Cyclic IMS System, gives scientists improved sequence coverage for native proteins and surrogate peptides and additional structural information about larger proteins that might not have been possible before.
For the first time, the new Desorption Electrospray Ionization DESI XS source is available on the Waters SELECT SERIES Cyclic IMS, SYNAPT™ XS, and Xevo™ G2-XS QTof Mass Spectrometers. Waters acquired the rights to DESI™ IP from Prosolia, Inc. and the Purdue Research Foundation in 2018, making Waters the exclusive provider of this technology. The new Waters DESI XS source retains the performance of the original version and features enhanced reliability and user experience, making high quality MS imaging accessible to a broader range of scientists.
The ECD and DESI XS options for the SELECT SERIES Cyclic IMS System will ship in the fourth quarter of this year. Existing Waters Cyclic IMS customers will also be able to add these new options to their instruments at the same time. DESI XS is now available to ship with new Xevo G2- XS QTof and SYNAPT XS Systems. It is also available as an upgrade option for previously installed Xevo G2-XS QTof and SYNAPT XS systems.
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INTERNATIONAL LABMATE - JULY 2020
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