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New High-Performance Liquid Chromatograph to Help Laboratories Meet Quality and Production Targets Introduced
Waters Corporation has introduced the Waters™ Arc™ HPLC System, a new high-performance liquid chromatograph (HPLC) for routine testing in the pharmaceutical, food, academic and materials markets. A key target application is quality control laboratories performing batch release tests on small molecule pharmaceuticals. Waters also announced the availability of Waters™ Empower™ BC LAC/E™ with SecureSync, its newly enhanced data back-up and recovery solution purpose-built for organisations with distributed laboratory environments.
The Arc HPLC System is for laboratories looking for a rugged, reliable and modern HPLC system that can run established HPLC methods regardless of the brand of liquid chromatograph on which they were originally developed, while preserving the chromatographic retention time reproducibility of those methods. The system offers ultra-low analyte carryover, superb injection precision and backpressure tolerance to 9,500 psi at 5.0 ml/min. It is designed to meet all the requirements of a top-of-the-line HPLC system in a cost-competitive package that takes routine testing to the next level.
“We designed the Waters Arc HPLC System exclusively for QC laboratories knowing how important trustworthy test results are to help ensure the uninterrupted supply of safe and effective medicines,” said Robert Buco, PhD, Director, Separations Technology, Global Product Management, Waters Corporation. “Arc HPLC is for customers who are ready to modernise legacy instruments while preserving their specifi c QC methods. Waters makes it simple, providing a unique two-injection method transfer capability from any brand of HPLC instrument onto the Arc HPLC System.”
“As a Waters customer for many years, we have standardised on Waters instrumentation and Empower software for testing,” said Bo Chen, Instrument Manager, Luoxin Pharmaceutical (Shanghai) Co., Ltd. “Their instrumentation has proven to be reliable and rugged and we know from experience that they stand by their products. The new Arc HPLC System appears to be highly suited for testing of fi nished products and we are eager to give it a closer look.”
More information online:
ilmt.co/PL/AeDL 52600pr@reply-direct.com
Faster Trace-Level Analysis of Acrylamide in Drinking Water and Food
Now available in two column formats for optimal application-specifi c performance, Allure Acrylamide LC columns enable you to meet method requirements for food and drinking water quickly and easily. Unique column chemistry reliably separates acrylamide from matrix interferences, and our new format for large volume injection lets you reach sensitivity requirements without time-consuming SPE preconcentration. The new 150 x 3.0 mm column provides an optimised balance of larger capacity and MS-friendly fl ow rates for large volume injection of drinking water samples while the original 50 x 2.1 mm format delivers faster analysis times and fewer column changes for both food and drinking water when used with SPE sample preparation. Pair with Restek guard columns and analytical reference standards to ensure data quality even down to low ppt levels in sample matrix.
Developed to withstand 100% aqueous mobile phases and elute coextracted matrix components rather than strongly retaining them, Restek Allure Acrylamide guard and analytical columns deliver the same robust performance injection to injection and column to column. The stringent manufacturing procedures and rigorous quality testing ensures that when it does come time to replace your Allure Acrylamide column, you will get the same great chromatographic performance with the new column that you relied on with the old one.
More information online:
ilmt.co/PL/RoqM 52077pr@reply-direct.com
Rugged Polysaccharide Chiral Columns
REFLECT™ chiral columns are rugged polysaccharide phases suitable for a large range of chiral compounds and are compatible with a wide range of solvents and separation modes (HPLC and SFC). High purity base silica and proprietary packing technology provide excellent peak shape and resolution when compared to leading chiral phases. High resolution greatly improves preparative loading, leading to greater productivity and higher purity separations. REFLECT™ chiral columns are fully scalable from 3 µm to 20 µm, and available in six different immobilised and coated phases.
REFLECT™ immobilised columns offer stability with strong solvents like THF, ethyl acetate and chlorinated solvents for greater fl exibility in developing separations that exhibit different selectivity in comparison with coated phases. The extended range of solvent choices can enhance sample solubility, which can have a positive effect on the production rate in preparative applications. REFLECT™ immobilised columns are available in Amylose A, Cellulose B, C, and J selectors.
REFLECT™ coated columns area made using a unique production process of coating the chiral selector on high purity silica gel and offer high effi ciency, with excellent peak shape and loading capacity. REFLECT™ chiral phases were developed to match or exceed performance of legacy polysaccharide chiral columns. REFELCT™ coated columns are available in Amylose A and Cellulose B selectors.
Regis has been a trusted supplier of high-quality chromatography products and unique chiral stationary phases for more than 45 years. All REFLECT™ chiral columns are affordably priced with fast delivery for most column sizes, including preparative. REFLECT™ analytical columns are guaranteed to match or exceed expected performance on a competing column of the same particle size, type and dimensions or your money back. Regis maintains a chiral applications database containing more than 900 applications as well as offering FREE chiral screening to fi nd a separation method for any chiral compound.
More information online:
ilmt.co/PL/Lpne 52167pr@reply-direct.com
New HPLC/UHPLC Methanol for Superior Chromatography Launched
Methanol, the simplest alcohol that exists, is a colourless, low-density, fl ammable and water-miscible liquid. Methanol and water have similar properties because both have hydroxyl groups that can form hydrogen bonds. These two solvents form hydrogen bonds with each other, being perfectly miscible in all proportions.
The high polarity of methanol makes it a very good solvent for polar substances. These characteristics make it one of the most used solvents in liquid chromatography. In this technique, the absorbance of the mobile phase is one of the critical points in the choice of solvent: the lower the absorption of the solvent, the greater the accuracy of the test and the better results under conditions of gradient elution. Scharlab launches its new Methanol Ultragradient (ME0339), the only HPLC methanol on the market that ensures minimal gradient absorption at 3 different wavelengths (230, 235 and 254 nm).
This new product, with the most restrictive specifi cations on the market, allows to carry out the most demanding analyses in the entire wavelength range. After passing an exhaustive Quality Control in their laboratory, Scharlab can ensure that Scharlau’s Methanol Ultragradient is the cleanest solvent with the lowest number of impurities, suitable for any chromatographic analysis.
Scharlab’s Methanol Ultragradient is also suitable for UHPLC. More information online:
ilmt.co/PL/Mpox
51437pr@reply-direct.com
INTERNATIONAL LABMATE - JULY 2020
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