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Chromatography 15


Glass Autosampler Vials Virtually Eliminate Surface Activity Reduced Surface Activity (RSA™) glass autosampler vials


are not coated vials and virtually eliminate the adsorption of basic compounds found with all other glass vials. The manufacturing process of RSA™ vials produces vials without surface activity such as basic compound adsorption. Unlike ordinary glass vials, these vials will not produce a pH change with aqueous diluent over time in the vial and with minimised surface metals, it is excellent for LCMS in that it does not contribute to sodium adducts.


Laboratories testing low abundance analytes such as low dosage form pharmaceuticals, unknown unknowns and natural products will see the greatest benefit even though all labs will find these vials to have value when repeating runs or investigations must be avoided.


The vials are available from MicroSolv Technology Corp in 12x32mm clear and amber with volumes of 2ml, 1.5ml and 300ul.


More information online: ilmt.co/PL/ZJGm 52069pr@reply-direct.com


Thriving in water


Fully wettable HPLC phase for analysis and purification


Bigger www.kromasil.com Choose the Right Chromatography for your Application


Selecting the right chromatographic column and media is essential for a successful separation and purification. Chromatographers just like you use Kromasil slurry packed columns and bulk from the early stages of screening and discovery to impurity isolation and API production because they can employ the same Kromasil stationary phase material across their pharma and biotech organisations. With Kromasil’s unique value proposition, you can have the methods transferred seamlessly, to colleagues working in different scales saving weeks even months and come to market faster.


Kromasil, a brand of Nouryon, is produced with perfectly spherical silica-based materials with particle sizes from 1.8 to 25 µm. The diagram illustrates where best to use Kromasil products in your daily work and select from the Kromasil Classic, Kromasil Eternity, Kromasil Chiral and Kromasil SFC platforms.


More information online: ilmt.co/PL/RDp1 50551pr@reply-direct.com


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Green Flash Purification System now Available with Five-Year Warranty Selekt greener flash purification system is now available with a five-year warranty. The Biotage®


A focus of the Biotage® Selekt system and Sfär consumables is to make purification greener by increasing the rate of purification whilst


simultaneously reducing solvent usage. The instrument’s high flow and the high-pressure capability enables purification to be performed at a faster rate. In parallel, the Biotage®


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Sfär complete portfolio of flash purification columns use spherical silica with a high surface area and


consequently a higher loading capacity – enabling chemists to select a smaller column to perform the same separation, reducing both the amount of solvent used and the cost of the separation.


More information online: ilmt.co/PL/DmnP 52275pr@reply-direct.com


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New Pre-packed Columns for Fast Method Development Introduced


Tosoh Bioscience GmbH, a provider of chromatographic solutions for the separation and purification of biomolecules, has announced the introduction of SkillPak 1 mL and 5 mL pre-packed columns. These process development columns are designed for fast method development and resin screening of monoclonal antibodies, antibody constructs, oligonucleotides, proteins, and viruses.


Pre-packed with TOYOPEARL® , TSKgel® or Ca++Pure-HA® process chromatography media, SkillPak 1 mL and 5 mL columns deliver


high performance and offer scalability and convenience - giving customers greater flexibility for use of process media from Tosoh. These columns are ready to use upon receipt and show excellent physical strength and ideal flow characteristics for industrial downstream processing.


SkillPak 1 mL and 5 mL pre-packed columns are available with short delivery times in affinity, anion and cation exchange, hydrophobic interaction and size exclusion chromatographic modes. Optimal performance is guaranteed with the columns and they can be operated directly with commonly used low or medium pressure liquid chromatography systems.


SkillPak 1 mL and 5 mL pre-packed columns are now available for sale in Europe, Africa and the Middle East from Tosoh Bioscience GmbH.


More information online: ilmt.co/PL/Lpx5 52332pr@reply-direct.com


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*Average Pass-on rate = 3.2


Quality and reliability is a hallmark of Biotage products, and the Selekt flash purification system is no different. Biotage is pleased to announce that the Biotage®


Selekt flash purification system


is a compact instrument with a small bench top presence, and features a large touch screen with intuitive controls that are easy to use reducing the time needed for training.


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Kromasil C18(w) is a wettable phase specifically engineered for bioseparations, API manufacturing and analysis. It can be loaded and run under 100% aqueous conditions, keeping excellent efficiency.


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