Proteomics, Genomics & Microarrays


PCR Cycler wins German Design Award 2018


Amplifying nucleic acids for further downstream processing is a cornerstone of modern molecular biology and medical research. This temperature dependent process needs utmost precision in temperature control. At the same time, the procedure needs to be as fast as possible, i.e. temperature changes need to be facilitated at high speeds.


The Mastercycler X50 from Eppendorf combines the capabilities of high speed (Heating of 10°C/s) with utmost precision (±0.15°C). High speeds, especially in cooling, can be supported by large heat sinks and strong ventilation. However, large footprints and strong ventilation noises need to be avoided in molecular biology labs. Thus, product design features like ventilating from front to back (and not to the sides where other instruments can be placed) and including powerful heat sinks in small footprints have to be brought to perfection.


The German Design Award 2018 acknowledges and honours Eppendorf’s strive for perfection in designing the Mastercycler X50. The highly esteemed and independent jury values unique design trends and pioneering contributions to the product design landscape.


For more information visit www.eppendorf.com/mastercycler. 44309pr@reply-direct.com IDO Pathway Products for Immunotherapy Drug Research


Amsbio offer a wide range of products for IDO pathway research, including cell lines, assay kits and active proteins to be used in IDO pathway research (IDO1, IDO2 and TDO genes).


Cancer cells use the indoleamine 2,3-dioxygenase (IDO) pathway to suppress the host’s immune response in order to facilitate survival, growth, invasion, and metastasis of malignant cells. The IDO pathway is active in many tumours, providing a direct defence against T cell attack. The IDO pathway also is active in many antigen-presenting cells, resulting in peripheral tolerance to tumour-associated antigens.


Amsbio offers a high-performance range of Inhibitor Screening Assay Kits designed to measure IDO1, IDO2 and TDO enzyme inhibition. These simple-to-use kits come in convenient 96- and 384-well microplate formats with enough reaction solution and enzyme to perform a total of 100 reactions.


In addition, the company has assembled a selection of stable recombinant HEK293 cell lines for monitoring IDO1 and TDO pathway activity and screening for activators or inhibitors of IDO1 and TDO in a cellular context. For studying enzyme kinetics, substrate specificity and screening inhibitors, Amsbio also offers a comprehensive range of Human and Mouse IDO1, IDO2 and TPO His-tagged proteins.


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Chromatrap® has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation (ChIP) assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded (FFPE) tissue.


Ideal for tissue samples, biopsies and difficult to lyse samples, the Chromatrap® FFPE ChIP-seq kit has overcome the issues often associated with FFPE ChIP, by offering a streamlined protocol which provides the user with excellent quality isolated chromatin.


The new updated Chromatrap® FFPE ChIP- seq kit protocol is shorter, offers increased chromatin yield / accessible epitopes and provides greater flexibility in chromatin sample loading for ChIP.


Innovative Solutions and Services for


Life Science Research • Analytical and Biological Products • Hydrogen Sulphide Related Research • Oxidative Stress Detection • Surface Modification • Cell Analysis • Kits for Life Science Research • Protein Analysis


For further details: Europa Bioproducts Ltd, 15-17 North Street Wicken, Ely, Cambridgeshire CB7 5XW


www.europa-bioproducts.com +44 (0)1353 721118 43231pr@reply-direct.com 14194EUR~1/2 PageAdvert-InnovativeSolutions2017(186x134).indd 1 8122ad@reply-direct.com 15/08/2017 10:16


The sensitivity of the unique Chromatrap® solid state platform ensures that small samples can be used with efficient enrichment of both high and low abundant targets. Chromatrap® FFPE ChIP-seq kits provide a quicker, easier and more efficient way of performing ChIP assays from a range of FFPE samples. Using the unique, patented Chromatrap® technology maximises the capture efficiency of the target chromatin/ antibody complex. By avoiding the use of magnetic or agarose beads, non-specific background is eliminated together with reduced manual handling errors and subsequent sample loss.


This kit is compatible with both qPCR and sequencing as a downstream process and has a wide dynamic range, ensuring that adequate DNA is enriched for library preparation for sequencing. The wide dynamic range of the Chromatrap® FFPE ChIP-seq kit enables better results from small sample sizes and provides greater flexibility. Prior to sequencing, DNA purification is required and Chromatrap® purification columns are supplied for ease of use.


Each Chromatrap® FFPE ChIP-seq kit contains sufficient Protein A or Protein G based spin- columns, buffers and reagents to perform 24 chromatin immunoprecipitation assays and up to 10 chromatin preparations.


FFPE ChIP-seq Assay Kit for Tissues, Biopsies and Diffi cult to Lyse Samples


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