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Patent Approval for Tandem Ionisation Announced has been approved.
Markes International has announced that its US patent (US 15/231,383) for Tandem Ionisation®
Tandem Ionisation is the latest extension of the company’s patented Select-eV® technology (US
Patent Number 9,524,858). Select-eV is the technology enabling acquisition of both reference- quality 70 eV spectra and repeatable ‘soft-ionisation’ spectra without the loss in sensitivity, use of chemical reagents or hardware changes that have historically been associated with soft ionisation. This award-winning way of producing both ‘hard’ and ‘soft’ EI mass spectra greatly speeds up the process of differentiating between similar compounds, such as structurally similar isomers and identifying unknowns.
Tandem Ionisation builds on the Select-eV technique by ‘multiplexing’ ionisation energies, allowing two sets of spectra to be simultaneously acquired across a single GC or GC×GC peak – both 70 eV spectra for spectral matching against commercial libraries, and the soft ionisation spectra.
Alun Cole, Founding Director at Markes International, said: “Since 2014, we have worked to establish soft EI as an essential component of the GC–MS toolbox and we are thrilled that the technology continues to gain momentum. With Tandem Ionisation, BenchTOF-Select is the only instrument capable of providing analysts with all the information required for reliable compound identification in a single GC or GC×GC run.”
The Tandem Ionisation patent has been approved in the US and is patent-pending in a number of countries across the world.
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Meet Manufacturers and suppliers of Petrochemical and Oil Analysis Instruments all in one place and at one time, compare products, technology and applications.
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Porvair Sciences reports that the National Center for Biological Sciences (NCBS) in Bangalore, India is using its Krystal 384 black microplate to produce a standard drug testing assay for Plasmodium vivax infection.
The NCBS is a leading national institute whose faculty members undertake research in the frontier areas of biology.
Scientists at the NCBS use experimental and computational approaches to study molecules, cells and organisms creating an understanding of the biology at each of these levels to advance an integrated view of life processes.
NOVEMBER 2017 - ANTWERP, BELGIUM NOVEMBER 2017 - ANTWERP, BELGIUM
In their research, the NCBS is using Krystal 384-well black microplates as the microenvironment to grow the cells infected with small numbers of parasites. Researchers are then treating the Krystal 384 black plates with different concentrations of drugs to check the effect on the infection and the development of the Plasmodium vivax parasites inside the cells.
Peftec 2017 is a focused international Conference and Exhibition for Industry professionals specialising in monitoring and analytical technologies for the Petroleum, Refining and Environmental Industries.
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Dr Mulaka Maruthi, a senior NCBS researcher commented: “Because they are manufactured to a very high flatness tolerance the Porvair Sciences Krystal 384-well black plates are very convenient to use with both our inverted microscope and High Content Screening machine. The clear plate bottom permits direct microscopic viewing or HCS imaging and the images are of high resolution.” Dr Maruthi added: “Using the Krystal 384-well black plates we have been able to minimise the number of cells for seeding, use smaller numbers of parasites, and lower volumes of drugs. Overall the Krystal 384 black plate has enabled us to perform these experiments in a single plate instead of many 96 well plates or other well formats.”
The Krystal 384-well microplate range incorporates novel square wells with a large liquid capacity of 120µl per well, increasing the achievable sensitivity of most HTS assays.
Using a proprietary manufacturing technique, the Krystal 384 offers market leading plate flatness (+/- 0.1mm tolerance) that translates into a significant increase in measurement precision and elimination of read errors when performing cell based assays using fluorescent or luminescent imaging.
All tissue-culture treated plates are supplied lidded and sterile, in individual bags.
For further information on the Krystal 384- well range please visit http://www.porvair-
sciences.com/en/services-menu/life-sciences/ clear-bottom-assay-plates/384-well-krystal/.
Microplate Enables Development of Drug Testing Assay for Plasmodium vivax
LABMATE UK & IRELAND - OCTOBER/NOVEMBER 2017
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