PREPARED FOR PFAS TESTING
Fast and High-Resolution LC-MS Separation with Ascentis® Express PFAS HPLC Columns
PFAS (Per- and poly-fl uoroalkyl substances) are persistent, man-made organic compounds, widely found in the environment. Recent awareness has brought attention to the toxicity of these substances. The U.S. Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA) have initiated actions against PFAS. For determination of PFASs, liquid chromatography–mass spectrometry (LC-MS) is a commonly used technique. The new Ascentis® Express PFAS HPLC column, with its Fused-Core® technology and a particle size of 2.7 µm, delivers fast and high-resolution separations with excellent selectivity, peak shape, and necessary retention to perform in EPA methods 537.1, 533 and 8327.
Key benefi ts of Ascentis® Express PFAS columns include:
• 2.7 µm Fused-Core® particle for reliable and high effi ciency separations and lower column back pressure compared to sub-2 µm particles
• Excellent suitability for MS detection
• Application-related Lot analysis and single column performance testing
• Pressure limit: 600 bar
Ascentis® Express PFAS HPLC columns enable precise MS results
The Ascentis® Express PFAS HPLC column is designed for the separation of novel and legacy short chain and long chain PFAS compounds containing branched and linear isomers, whilst adhering to EPA methodology requirements. Furthermore, a specifi c PFAS delay column prevents background PFAS contamination from interfering with the sample results in quantitative LC-MS methods.
The highly retentive endcapped silane of the Ascentis® Express PFAS Delay column provides high retention of PFAS compounds across various mobile phase conditions and is used to delay background instrument PFAS contamination from interference with analyzed samples. For this reason, the Ascentis® Express PFAS Delay column is placed upstream of the sample injector and after the mixer.
Analysis of PFAS Compounds in EPA 537.1:
IET SEPTEMBER/OCTOBER 2021
WWW.ENVIROTECH-ONLINE.COM
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