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Environmental Analysis 51 EVOQ – The Science of Sensitivity


The elliptical ion path of Bruker’s new mass spectrometry triple quadrupole (MS-TQ), has several aspects adding to the overall sensitivity. The innovative detector eliminates the need for a conversion dynode, which allows for highly sensitive negative ion detection and fast switching capability. The Bruker patented lens- free ion path improves MRM sensitivity by significantly reducing ion scattering losses in the quadrupoles before and after the collision cell. The EVOQ orifice interface design ensures that the ions traverse the opening into the vacuum chamber and come under the influence of the IQ dual ion funnel system in the fastest time possible. The vital requirement for high- sensitivity is simply to minimize the time spent going from the spray chamber into the IQ dual ion funnel in the first vacuum region.


Reader Reply Card No.


Tune-free Ion Optics An elegantly simple


tune-free ion optic design captures ions in the free- jet expansion region and efficiently focuses them into a coherent ion beam to deliver high sensitivity and robustness without the need for compound-specific tuning.


Reader Reply Card No. 239


Performance-driven PACER Software


THE SCIENCE OF SENSITIVITY 238


EVOQ Delivering Heat Where it Belongs


EVOQ, the new MS-TQ from Bruker, allows you to let VIP technology take over. The responsibility of ensuring precise heated the electrospray ionization (ESI) for maximum sensitivity. VIP, a patent-pending heated ESI design, that efficiently ionizes thermally labile molecules such as N-oxides, glucuronides, or peptides during the high flow rate heated ESI process. This innovative technology provides an insulated flow path for the LC eluent shielding it from undesirable temperature fluctuations occurring during the LC gradient.


• High-efficiency ceramic heater technology, with configured thermal profiling, delivers the highest heat near the probe tip.


• Shaped vacuum insulation protects the LC eluent from boiling before nebulization. • Fluid path remains cool before nebulization, which is essential for protecting thermally fragile compounds.


Reader Reply Card No. 237


For years instrument manufacturers have delivered hardware that promised to run more samples per day, using automated sample preparation and ballistic gradients. But productivity did not increase. Why? Vendors forgot that the vital process of data analysis and review was still dependent on redundant levels of human interaction to ensure data quality. They simply shifted the bottleneck and in the process failed to satisfy the need for increased efficiency. Hardware is only half the solution, previous solutions left users drowning in data.


With the Bruker’s new EVOQ™ comes an innovation in software with the new PACER™, making the human interaction with the process of data review more efficient by eliminating data review bottlenecks. This is undertaken by employing exception-based data review to instantly highlight integrated peaks that fail to meet the preset method criteria, so the analyst can now focus on the problem areas. This software innovation instantly increases efficiency by eliminating unproductive time spent on data review without compromising data quality.


In a commercial testing laboratory time is critical and data quality is paramount. PACER software and the EVOQ LC-TQ enable you to run more samples without the typical data analysis bottlenecks.


Reader Reply Card No. 240 Reader Reply Card No. 241 www.envirotech-online.com IET September / October 2012


The EVOQ liquid chromatography triple quadrupole (LC-TQ) was designed for a singular purpose – to reliably quantify thousands of real samples in the fastest sample-to-report time possible. It delivers exceptional sensitivity, precision, accuracy, linearity, and a wide dynamic range for your multiple reaction monitoring (MRM) assays. Innovations in software and atmospheric pressure ionization (API) technology make it a game changer for routine high-sensitivity, quantitative analysis.


Highly efficient VIP heated electrospray and APCI probes UHPLC, HPLC or OLE modules with built-in oven and degasser Superior MRM sensitivity lens-free mass analyzer Flat-tuning, tune-free, IQ dual ion funnel Orifice Interface for high sensitivity and robustness Performance-driven PACER software


Visit www.evoqms.com for more information. Innovation with Integrity


Introducing the EVOQ Qube and the


EVOQ Elite LC-TQs from Bruker


MASS SPECTROMETRY


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