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Custom-Designed CGH Microarray


Agilent Technologies, Inc announced that scientists using an Agilent custom-designed comparative genomic hybridization (CGH) array have sequenced the entire gene map of a Korean male. An international team led by researchers at Seoul National University published the results in Nature.


The study, ‘A highly annotated whole-genome sequence of a Korean individual’, is the second Korean genome to be sequenced in recent months and the seventh complete human genome to be published in the past two years.


The Seoul National University team used several complementary approaches to detect CNVs, including an Agilent custom-designed CGH array with more than 24 million probes.


The team initially identified 1,237 CNV regions, but used conservative criteria to cut that down to 238 deletions ranging from 277 bases to 196,900 bases and totaling 2.4 megabases, and 77 copy number gains, totalling 7 megabases.


Of these CNVs, 148 of the deletions and 33 of the gains were not in the Database of Genomic Variants and are considered to be novel.


Agilent's custom microarrays offer the flexibility and accuracy needed to detect CNVs. The platform offers high-quality long oligonucleotide catalog and custom arrays to interrogate any genome at high- resolution and accuracy.


Agilent's custom arrays allow users to easily select the regions of the genome (or the entire genome) they want to target. With 28.7 million in-silico- validated probes available in eArray, Agilent's online tool for design custom arrays, researchers can choose what regions, resolution and array format they want for a given study.


Custom arrays are available in all eight formats (1x1M, 2x400K, 4x180K, 8x60K, 1x244K, 2x105K, 4x44K and 8x15K), from Agilent at no additional cost to the user.


Circle no. 367 Circle no. 368


New Water Purification Systems


Human Corporation have introduced their new water purification systems, TOC monitoring and EDI (Electrodeionisation), welding together cutting-edge technology and art design.


For a better way to get your message across...


The water purification system (TOC) can monitor TOC and pressure combining with existing factors - feed water conductivity, temperature and UP water resistivity. It is an excellent solution for users who want to check real-time TOC in their UP water with sustained accuracy, precision, and reliability as it removes the need for separate costly TOC meters.


The EDI system operates without the requirement of any exchange of ion filter packs,


even though it produces high quality water (10~15 MΩ•㎝). It uses a combination of ion- selective membranes and ion-exchange resins, sandwiched between two electrodes under a DC voltage potential to remove ions from RO-pretreated water.


EDI is simple and compact, provides water of consistent quality, cost-effective and eco-friendly. Contact: sales@intlabmate.com Circle no. 369


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