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30


September 2009


Breakthrough in Autosampler Technology


These elegantly effective AutoQuest autosamplers are specially designed for use with the Cecil Adept HPLC, Q- Adept HPLC and IonQuest Ion Chromatography Systems. They may


also be used with third party LC systems.


Available with 50 or 100 sample positions, these autosamplers from Cecil Instruments provide for ultra low carryover, ultra high injection precision, priority sampling, replicate injections and sample volumes from5 µL to 2mL.


The ultra low carry-over provides for the ultimate in effective sampling for trace residue analysis, impurity determinations and contaminant levels.


Easy and reliable use is via PC control or the stand-alone keys.


The AutoQuest autosamplers fit neatly with the Adept HPLC,Q-Adept quaternary HPLC and IonQuest Ion Chromatographymodular systems.


Each Chromatography system is designed to achieve long-term, fast and reliable measurements, with ease.


Because the systems are modular and versatile, different detectors may be accommodated depending on analytical requirements. These detectors include variable wavelength UV/Visible, WaveQuest UV/Visible, electrochemical, refractive index, conductivity and fluorescence. Each detector is of the highest industry specification and is renowned for its Ultra-Low Drift.


Comprehensive, versatile, intuitive and easy to use PowerStream software provides for 21 CFR part 11 compliance.


For more details, please contact: info@cecilinstruments.com http://www.cecilinstruments.com/adept-autosamplers.html


Top Ten pharma Company Uses Automated TLC Plate Reader To Ensure the Contents of Drugs and Raw Materials are Safe


Syngene is pleased to announce the first ChromaScan automated non-radioactive TLC plate reader is being used in the main manufacturing facility of a major pharmaceutical company, to improve the accuracy of its drug testing.


The manufacturing plant in the UK is responsible for the worldwide supply of a range of therapies and is using the ChromaScan system to automatically image fluorescent and visible TLC plates to test samples for purity, stability and content uniformity. The samples tested include treatments for hypertension, arthritis and epilepsy, as well as the raw materials used in the manufacture of these drugs. Using an automated system is helping to ensure the results are both reproducible and more accurate, which will in turn assure the content of each batch of drugs is safer.


Laura Sullivan, Syngene’s Divisional Manager commented: “We are delighted our ChromaScan system has been assessed so positively and is now being routinely used in one of the best pharmaceutical manufacturing facilities in the world. Their confidence in our new TLC plate reader’s performance is a great endorsement because it shows scientists wanting to automate TLC analysis in a quality driven environment that ChromaScan is a perfect choice.”


Web site: www.syngene.com Analysis of ProducedWater Contaminants by Ion Chromatography


Drilling for oil or gas holdsmany challenges. Keeping pipes free of scale deposits is one of them. This involves themonitoring of ionic components in produced water, a task that is best handled by ion chromatography (IC).


Producedwater iswater trapped in underground reservoir rocks and is brought to surface alongwith the crude oil and gas. Besides dispersed oil droplets and dissolved organic compounds, producedwatermainly contains significant amounts of inorganic cations such as calcium,magnesium, bariumand strontium, and anions such as carbonate, bromide and sulfate. Precipitation of the corresponding salts often leads to the formation of scale deposits that can clog pipes.


For this reason it is of paramount importance to determine the inorganic constituents of produced water in order to choose the correct dosing of scale inhibitors.While the anions bromide, sulfate, acetate and butyrate can reliably be determined by suppressed conductivity detection, the cationsmagnesium, barium and strontiumare determined by non-suppressed conductivity detection.


Of the numerous analytical techniques for the determination of ionic species, IC is the best suited in terms of selectivity, flexibility, automation and ruggedness. Take advantage ofMetrohm’s complete offer of IC systems and stay on course to reach your production goals.


For further information please contact Metrohm UK Ltd Tel 01280824824 or Email your requests to enquiry@metrohm.co.uk


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