PHARMANORD
100 mg capsules of Bio-Quinone Q10, while the other half got the same amount of identical dummy capsules with an inactive placebo. The patients in both groups continued with their regime of medicine that is normally prescribed for heart failure.
After two years, there were 43 per cent fewer heart-related deaths in the Q10 group. In addition, there were 43 per cent fewer heart-related complications among the Q10- treated participants, including among other things hospitalization due to worsening of the heart failure. The research documents that coenzyme Q10 is able to improve symptoms and course of disease in patients with heart failure. Patients who were given coenzyme Q10 had a signifi cantly lower mortality rate.
This research is supported by the KIESL-10 trial in which 440 individuals aged 70-88 years, received either a placebo or 200mg of Bio- Quinone Active Q10 and 200mcg of SelenoPrecise daily for fi ve years. Supplementation with this specifi c Q10 and selenium improved heart health and reduced the risk of cardiac
related mortality by more than 50%. In addition a heart stress biomarker (NT-proBNP) increased in the placebo group by over 20% in 48months but remained unchanged in the treatment group.
The quality and bioavailability of the Q10 used in these trials was key to the effi cacy of the supplement and in turn the results.
THE IMPORTANCE OF BIOAVAILABILITY
Bioavailability is defi ned as the proportion of an ingested substance that is absorbed from the digestive tract into the bloodstream. For the impact of CoQ10 to be felt, the bio-availability of the supplement is fundamental. To have an impact the coenzyme must be effectively absorbed and used by the body, raising blood Q10 levels to a suffi cient level.
The only objective measure of bioavailability comes from data obtained in clinical studies of human subjects, as documented in the medical literature.
CoQ10 when fi rst supplied is in the
form of orange crystals, which cannot be absorbed from the digestive tract. A patented method is then used to disperse the CoQ10 crystals into single molecules, which can then be absorbed. Because CoQ10 is a lipid soluble substance, the crystals are dispersed in a carrier oil, as this aids absorption. However there is a common misconception that mixing CoQ10 with a carrier oil is suffi cient to facilitate absorption; as noted above the crystals must fi rst be dispersed, and equally importantly must not reform during the product shelf-life.
It should also be noted that CoQ10 in its naturally occurring form cannot be made more water soluble- any structural modifi cation means the molecule is no longer CoQ10.
OXIDISED AND REDUCED FORMS OF COQ10
CoQ10 occurs in the body in two forms, oxidised (ubiquinone) and reduced (ubiquinol). These forms undergo continual inter-conversion as part of the normal functioning of CoQ10, and neither form is more important than the other.
Most people are able to suffi ciently absorb CoQ10 in its oxidised (ubiquinone) form, and this is the form on which most randomised controlled clinical trial studies have been based. In this regard, there have been more than 90 clinical trial studies that have used Bio- Quinone CoQ10, confi rmating the bioavailability, effi cacy and safety of this product.
Supplementation with the reduced (ubiquinol) form of CoQ10 may be benefi cial in people with impaired digestive absorption, for example those with irritable bowel syndrome or the elderly. Relatively few clinical trials have been carried out to date using the ubiquinol form of CoQ10. It should be noted that ubiquinol is extremely sensitive to the effect of air and light. Some products claiming to contain ubiquinol in fact contain ubiquinone – this can be determined by cutting open the capsule; ubiquinol should be white in colour whereas ubiqinone is yellow.
Visit
www.q10.co.uk for more information.
1 Q10
REACH THE TOP WITH
GOLD 100mg
If you haven’t yet experienced the full benefit of coenzyme Q10 the Q10 Starter Pack gives you the perfect opportunity to try the original Q10 formula!
Well done Noel and Lynne!
Northern Ireland’s Noel and Lynne Hanna have become the first couple to summit Mt. Everest from both sides, using Bio-Quinone Active Q10 for energy and endurance!
To place an order call 0800 591 756 or for advice visit
www.pharmanord.co.uk
Product
Noel and Lynne Hanna on top of Mt. Everest with Pharma Nord flag
Bio-Quinone Q10® Starter Pack - 100mg
Pack Size 20 caps
Trade (£) ex. VAT
8.12
RRP (£) inc. VAT
14.65 4
Official reference product for
International Q10 Research
5 98%
of Pharma Nord Q10 users recommend it!*
PHARMACY IN FOCUS - 15
Over 25 years of research and development
2 Safety
documented in over 90 clinical trials
3
Proven to raise blood Q10 levels
*Consumer survey, 3413 Q10 users, Pharma Nord Feedback Cards
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64