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your horse up to two of the allowed NSAIDS at a show. If you use only one then you do not need to file a medication report. If you use two then you must fill out a report. Starting December 2011 you may only use one NSAID at a show. Of the allowable NSAIDS such as Bute, Banamine, Ketofen, Naproxen, Surpass and Equioxx, any two may be used with the exception that Bute and Banamine may not be used together at the same show.


Equioxx What is new is information regarding Equioxx or firocoxib. Equioxx differs from medications like Bute, Banamine, and Ketofen in that when used, as I am about describe it, it can provide 24 hour anti-inflammatory effects vs. 12 hours for the other drugs and still comply with USEF medication rules. The advantages of this should be clear. You can obtain anti-inflammatory effects you want during the show. (With Bute and Banamine which must be used 12 hours prior to showing, and whose effects lasts about that long, the medication’s benefits wane just as you are about to compete.)


first day you use it; you need to use it at three times the regular dose. Equioxx is dispensed in paste form, and you would give three pastes all at the same time the afternoon of the first day of treatment. Then each afternoon of the show give an additional dose of the medication based on your horse’s weight. As the diagram shows, in this way you will maintain a blood level that is above the therapeutic level but below the USEF maximum allowable level.


you can use it and have no need to use a second drug such as Ketofen to obtain 24 hour anti-inflammatory effects. In the end that will also save on cost. Starting with the rules at the end of 2011, and going forward, it makes a lot of sense to use Equioxx given that the use of only a single NSAID will be permitted.


For 2011 using Equioxx makes sense, The key to using Equioxx is that the


For the rest of 2011, you can give


important….. Equioxx will basically not have the 24 hour effectiveness without it. Used at the standard dose of 1 tube/day for a full sized horse it takes 8 days to reach the steady state of blood levels that will be achieved by using the triple dose on day one. Of course if your horse has already been getting Equioxx for many days prior to the competition you do not need to give the triple dose on the first day.


A compelling reason for using Equioxx paste is the nature of the drug itself. It is a COX-2 selective inhibitor. All the other NSAIDS currently permitted, like Bute and Banamine, block both the COX-1 and COX-2 pathways when administered. Equioxx blocks only the COX-2 pathway and not the COX-1 pathway.


is what you want; it relieves pain and reduces inflammation. Blocking the COX-1 pathway can potentially harm your horse resulting in increases risks of side effects such as gastric ulcers, intestinal inflammation and kidney disease.


Previcox Many have asked why not use Previcox, the small animal pill version


Blocking only the COX-2 pathway


Why using the triple dose is


of firocoxib instead. The reason I recommend using Equioxx paste at horse shows at this time is that the protocol I just described has been well tested in horses. The research is clear.


has tested the Previcox pills in horses. It may be that they work exactly as well in the horse as the Equioxx paste, or it may be that they are poorly absorbed or cause a high spike in blood levels of firocoxib which will exceed USEF limits. No one knows because no one has done the research. At least for now I would stick to Equioxx at the horse shows. By using the paste you also know for sure that your horse got all of his medicine in the right amount.


FEI Competitions What makes Equioxx very useful for USEF horse shows? It is important to monitor if you are competing in international level competitions governed by the FEI’s more restrictive medications rules. Because Equioxx will be cleared very slowly from your horse for FEI competitors it is recommended that you not use Equioxx for 30 days prior to a competition.


begun. Enjoy. I will see you out there with my horse, Kolor Me Fabulous!


The horseshow season has just On the other hand absolutely no one


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