MICROSCOPY 77
Fig. 2. Modern systems enhance the cell culture workflow. Standardisation, efficiency and documentation are enabled by Olympus cell culture solutions, including the CKX53 cell culture microscope, CKX-CCSW cell confluency checker software and automated cell counter R1
have incorporated a number of features to overcome these challenges, from the ability to fit inside the clean bench, to novel optical techniques (Fig. 2.).
With the latest optics, cell culture microscopes facilitate
fast and efficient screening, and feature a large field number to expand the field of view. Tis allows easy inspection of multiwell plates, which is ideal for cell cultures in a variety of different microplate formats.
Te most popular
illumination method for cell culture observation, Phase Contrast has also now been optimised. Allowing fast and high contrast observation of phase objects, a new integrated Phase Contrast (iPC)
With improved image quality and ergonomics, the CKX53 delivers excellent performance for a variety of cell culture needs including live cell observation, cell sampling, image capture and fluorescence observation
Fig. 3. The cell growth phase. Cell proliferation begins in lag phase, turning into the exponential log phase as growth factor concentration increases. Growth plateaus as nutrients are consumed, and increased cell density leads to contact inhibition
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