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ANALYTICAL AND LABORATORY EQUIPMENT 19


Containment technology also off ers easy cleaning with a small area and no fl oor to wash, which is simple to validate as operations are repeatable. Isolator systems allow the use of solvents for cleaning and can be sterilised to reduce any bacterial contamination. Reduced cross- contamination is also achieved via the elimination of operators within the same environment as the materials.


A closed set-up also makes it more eff ective and ergonomic to contain the operation instead of wrapping the operators up with full suits and head covers, whilst handling products and instrumentations easily through the glove ports. And improved operator safety is enabled by removing the operator from the same environment as the operation (such as fi lling) occurs.


Another advantage is that containment technology represents a fully automated


system to control all utilities and environmental conditions. As well as this, it off ers lower capital expenditure with a greatly reduced footprint – and in many cases containment technology is less expensive than a cleanroom to purchase and install. Overall, such systems off er a lower operating cost with less maintenance but also reduced or even eliminated gowning and de-gowning time.


Isolators also reduce energy costs One fi nal advantage is that of 35% to 50% lower energy costs as isolators generate less utility consumption thanks to a small space to contain and small air fl ow capabilities.


Overall the benefi ts of containment technology provide a much superior sterility assurance and cost savings. With the trend of higher potency and purity of pharmaceutical and biopharmaceutical compounds,


containment technology is becoming the norm. Since operators need to limit their exposure to these products, handling operations must be carried out inside the isolator. Using glovebox technology eliminates any possible operator contamination of the compound or process as the operator never has direct contact with the product. T is is one of the main advantages of such systems as human interaction is the most diffi cult parameter to control.


Containment technology has vastly changed over the past fi ve years and these systems can accommodate integrated equipment, providing set environments, operator and product protection for a very competitive investment.


For more information ✔ at www.scientistlive.com/eurolab


Michelle Frisch is senior manager, Global Technical Systems at Powder Systems Limited (PSL). www.powdersystems.com


How different is the difference?


Aerospace manufacturer, Essex Cleanroom suite


In cleanrooms and other highly controlled environments, the precise measurement and fast response to differential pressure changes is crucial. Rotronic pressure sensors meet this requirement with accurate and stable analogue and digital outputs, with relay operation. www.rotronic.com


For more information ✔ at www.scientistlive.com/eurolab


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