YOUNG CATTLE R A I S E R S
ANADA 200-495, Approved by FDA Enroflox 100 (enrofloxacin)
100 mg/mL Antimicrobial Injectable Solution
For Subcutaneous Use in Beef Cattle, Non-Lactating Dairy Cattle and Swine Only.
Brief Summary: Before using Enroflox 100, consult the product insert, a summary of which follows.
CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. Federal (U.S.A.) law prohibits the extra-label use of this drug in food producing animals.
PRODUCT DESCRIPTION: Each mL of Enroflox 100 contains 100 mg of enrofloxacin. Excipients are L-arginine base 200 mg, n-butyl alcohol 30 mg, benzyl alcohol (as a preservative) 20 mg and water for injection q.s.
INDICATIONS: Cattle: Enroflox 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in beef and non-lactating dairy cattle.
Swine: Enroflox 100 is indicated for the treatment and control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis and Streptococcus suis.
Enroflox 100 is administered as a single dose for one day (swine) or for multiple days (cattle) of therapy. Enroflox 100 is not approved for a one-day, single dose of therapy in cattle.
Swine: Animals intended for human consumption must not be slaughtered within 5 days of receiving a single-injection dose.
Cattle: Animals intended for human consumption must not be slaughtered within 28 days from the last treatment. This product is not approved for female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
RESIDUE WARNINGS:
HUMAN WARNINGS: For use in animals only. Keep out of the reach of children. Avoid contact with eyes. In case of contact, immediately flush eyes with copious amounts of water for 15 minutes. In case of dermal contact, wash skin with soap and water. Consult a physician if irritation persists following ocular or dermal exposures. Individuals with a history of hypersensitivity to quinolones should avoid this product. In humans, there is a risk of user photosensitization within a few hours after excessive exposure to quinolones. If excessive accidental exposure occurs, avoid direct sunlight.
PRECAUTIONS:
The effects of enrofloxacin on cattle or swine reproductive performance, pregnancy and lactation have not been adequately determined.
Not for Use in Female Dairy Cattle 20 Months of Age or Older Or In Calves To Be Processed For Veal.
Riding for the Brand
By Kim Smith, Texas and Southwestern Cattle Raisers Foundation
P
ASSIONATE ABOUT THE WESTERN LIFESTYLE, multi-talented entertainer Red Steagall
is well known for his music and poetry that speaks of the cowboy and his way of life. Somewhere along the way he came up with the idea to combine fi rst-rate ranching pho- tography with his stage performance. The result is a multimedia treat that engages the senses and touches the heart. Thanks to Red, last month the Texas and
Southwestern Cattle Raisers Foundation hosted a special evening with “Ride for the Brand,” a show that celebrated the heritage and culture we hold so dear. As evidence both of Red’s creativity and generosity, he put the show together and performed along with fellow friends and musicians Don Edwards, Jean Prescott, Dan Roberts and the Boys in the Bunkhouse. Guests enjoyed wonderful music and poetry performed against a back-
The long-term effects on articular joint cartilage have not been determined in pigs above market weight. Subcutaneous injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter.
drop of spectacular photography by renowned western photographers Wyman Meinzer, Texas state photographer; Bob Moorhouse, retired general manager and current member of the board of directors of the Pitchfork Land and Cattle Co., whose photographs form the basis of the American Quarter Horse Heritage Center and Museum’s fi rst traveling exhibit and grace the pages of numerous magazines; and David Stoecklein, recognized by the editors of True West magazine as the “Best Living Photographer of the West” for the past 4 years. The featured photographers have spent years documenting ranch life
Enroflox 100 contains different excipients than other enrofloxacin products. The safety and efficacy of this formulation in species other than cattle and swine have not been determined.
Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders. In such animals, quinolones have, in rare instances, been associated with CNS stimulation which may lead to convulsive seizures. Quinolone-class drugs have been shown to produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in immature animals of various species. See Animal Safety section for additional information.
ADVERSE REACTIONS: No adverse reactions were observed during clinical trials.
ANIMAL SAFETY:
In cattle safety studies, clinical signs of depression, incoordination and muscle fasciculation were observed in calves when doses of 15 or 25 mg/kg were administered for 10 to 15 days. Clinical signs of depression, inappetance and incoordination were observed when a dose of 50 mg/kg was administered for 3 days. An injection site study conducted in feeder calves demonstrated that the formulation may induce a transient reaction in the subcutaneous tissue and underlying muscle. In swine safety studies, incidental lameness of short duration was observed in all groups, including the saline-treated controls. Musculoskeletal stiffness was observed following the 15 and 25 mg/kg treatments with clinical signs appearing during the second week of treatment. Clinical signs of lameness improved after treatment ceased and most animals were clinically normal at necropsy. An injection site study conducted in pigs demonstrated that the formulation may induce a transient reaction in the subcutaneous tissue.
Norbrook Laboratories Limited Newry, BT35 6PU, Co. Down, Northern Ireland
I02 Mar 2013
from a uniquely informed perspective. Their work has been showcased in a variety of magazines, museums and galleries around the world, bring- ing positive attention to the rugged independence of the cowboy and the beautiful landscapes that benefi t from their stewardship. Once the ranching community saw the quality of work and the respect
shown to the working cowboy, the photographers were granted unparal- leled access to numerous ranches. The resulting photographs are nothing short of stunning. TSCRF thanks the musicians and photographers alike for a wonderful
musical and visual tribute to the cowboy and ranching way of life. Red, never idle, began a new show on RFD-TV this year called “Red
Steagall Is Somewhere West of Wall Street.” In launching the show, he said, “My Quarter Horse Grey Dog and I are
off to explore the people, places and stories of the American West. We will visit museums that present and perpetuate the image and lifestyle of the American West.” Red, long-time friend of the Foundation, taped a segment at the Cattle
Raisers Museum, so watch for his show that airs weekly on Monday eve- nings at 8:30 p.m. CST.
32 The Cattleman April 2014
thecattlemanmagazine.com
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