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Those who take Nembutal for a peaceful death are often taking other drugs for various health problems. When approaching the chosen time to take the Nembutal, the question is often asked about whether any intercurrent medications should cease.
There are only a few drugs that interfere with the action of Nembutal, and there is generally no need to cease taking other drugs in the preceding days. Nevertheless, it is common practice for those planning their death to cease all but the essential medication in the week before their planned exit.
Chronic heavy alcohol use can lead to cross-tolerance and impair the action of the barbiturate. In rare cases, taking another barbiturate, such as the anti-convulsant phenobarb, can lead to the development of a barbiturate-tolerance. In these cases, a larger dose of the Nembutal (12gm powder or 2 x 100ml bottles) would be advised.
Some drugs enhance the effect of the Nembutal and can even be employed for that specific purpose. An example is the anti- convulsant Dilantin (phenytoin sodium Fig 15.11).
Dilantin is useful as the drug dissolves in water forming an alkali solution which is compatible with the liquid Nembutal. Nembutal of uncertain quality can have its potency enhanced by dissolving 1- 2gm of phenytoin sodium in the solution before drinking. This process is shown in the accompanying video “Making Nembutal even more effective”.
Although Dilantin is a drug that is controlled, it is relatively easily obtained through Internet mailing sources. It is not a drug that attracts attention.