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A lethal blood level of the drug, requires quantities in excess of 5gm. 250mg chloroquine phosphate tablets have ~150mg of active chloroquine base, so anything in excess of 2 packets (40 x 250mg tablets) would be lethal.
The drug is taken by mouth whereby it is rapidly and com- pletely absorbed from the gut. Administration involves crush- ing 50 tablets and then dissolving them in 100ml of water. This method will lead to rapid absorption. However, this small drink will be extremely bitter.