PREMIER TEAM SCALES HEIGHTS
FOR FARMERS IN NEED A team from Premier Nutrition will be donning their walking boots as they prepare to tackle the Three Peaks Challenge, in aid of the Royal Agricultural Benevolent Institution (RABI). The team of 21 hikers, and four drivers
is set to take on the three highest mountains in England, Scotland and Wales, covering a distance of 23 miles and an ascent of 3,064 metres, starting at the foot of Snowdon on 21 June 2019. Premier Nutrition support nutritionist,
Hannah Barber, who is heading up the group, explains that she has high hopes to finish the challenge in just 24 hours. “We’re aiming to complete the first leg on
the Friday evening, so we can drive through the night to reach Scafell Pike before sunrise, allowing enough time to complete the final Ben Nevis leg by 6pm on the Saturday evening,” she says. “It’s going to be a huge challenge for the
team, but it’s nothing compared to the hardship of the individuals that RABI supports. “The charity works tirelessly to provide
financial support to aid farming families in times of need. As we all work in the agricultural industry, this is something that’s close to our hearts, and we’ve set a target to raise over £2,000 for the important cause,” says Hannah.
ADVANCIA ACADEMY FOCUSES
ON BUTYRATE More than 125 participants attended the first 2019 Advancia Academy, which was held in Rome on April 2nd and organised by Adisseo, prior to the 6th International Conference on Poultry Intestinal Health. All presentations and questions will be available on
www.feedchannel.online Rome was hosting the 6th Intestinal
Health Scientific Interest Group IHSIG now called the International Conference on Poultry Intestinal Health. Adisseo’s Advancia Academy 2019 focused on butyrate. “Butyrate is indeed an essential nutrient for the intestinal epithelial cells and hence offers gut health benefits. It can either be produced by commensal bacteria or supplemented through the diet. What are the benefits and limits of its action? How can we improve gut functioning through endogenous and exogenous butyrate are the key topics of this Advancia Academy” said Dr Pierre-André Geraert, (Director Scientific Marketing, Adisseo).
Butyrate: a key functional regulator To open the seminar, Dr Hervé Blottiere from INRA & Micalis France revisited the fundamental roles of butyrate for the intestinal mucosa, commenting: “Dysbiosis or gut disturbance is often associated with decreased of genes and bacteria linked to butyrate production. Butyrate appears essential in gut physiology, is involved in cell metabolism, barrier function, gut motility, endocrine functions and immune regulation. Its new role as a potent activator of AhR nuclear transcription factor makes butyrate an important modulator in intestinal epithelial cells.”
Dr Petra Louis from The Rowett Institute Donations are being collected through
JustGiving and progress can be followed on Twitter: @ruminantpremier and LinkedIn: Premier Nutrition (UK).
addressed the gut microbial short-chain fatty acid metabolism through the human microbiota example. How the microbiota is influenced by the dietary substrates, particularly fibres, and how bacteria feed each other. Those metabolic pathways are key elements which could help to better feed our animals taking into account the microbiota.
From stimulating the butyrogenic microbiota to the optimal dietary form of butyrate Prof Filip van Immerseel from Ghent University focused on the dietary means to influence the butyrogenic microbiota in poultry gut through for instance, the prebiotic effect of arabinoxylan oligosaccharides as well as the benefit of supplementing dietary butyrate to reduce pathogen shedding (Salmonella sp, Clostridium perfringens). Dr Joshua Gong illustrated the importance of supplementing protected form of dietary butyrate. Butyrate also appeared to decrease lipid deposition through reducing the lipogenic pathways. It also stimulates beneficial bacteria in the hindgut. Prof Kolapo Ajuwon from Purdue
university further addressed the action on butyrate on the gut and beyond showing in particular the effect on gut-brain axis and also its epigenetics benefits. He also illustrated the importance to adapt butyrate supplementation according to specific growth or challenging phases (weaning, heat stress…) faced by the animals. To close the seminar, Dr Jean-Paul
Lalles (INRA) opened the field through the molecular and functional aspects of butyrate and its effects on Intestinal Alkaline Phosphatase and inducible Heat Shock Proteins important players in gut protection against inflammation. The overall messages of the seminar
revealed the importance of butyrate both produced by commensal bacteria as well as supplemented through the feed. Its role as a nutrient is well known but more roles as messenger for good gut function have been extensively demonstrated: from cell proliferation and differentiation, better gut frontier integrity, improved gut immune function and even effect on the local and central nervous system.
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