COAGULATION
Each case can involve multiple assays across different methodologies, often with short turnaround expectations. This diversity necessitates platforms that can deliver flexibility and precision without disrupting overall workflow
be automatically captured and linked to analyser performance metrics, simplifying documentation for method verification. Internal quality-control results were displayed with real-time trend analysis, enabling laboratories to detect shifts before they breached predefined limits. And for audits and accreditation reviews, the system generated structured reports, audit trails, and performance summaries that aligned with typical inspection requirements.
function is essential. Staff involved in the evaluation noted that the platform operated reliably under these demands, without bottlenecks caused by unavailable channels or reagent reload delays.
Reflex testing was another critical
factor. Using internal rules configured in the sthemE Manager data system, assays could be automatically reflexed based on initial results. In contrast to systems that require manual removal and reloading of samples, this automation streamlined routine workflows and reduced the risk of technical error, allowing results to be delivered faster and with greater consistency.
Another specific focus during the evaluation was the automation of mixing studies – a traditionally manual process used to investigate prolonged APTT results and differentiate between factor deficiency and the presence of a lupus anticoagulant or specific inhibitors. By configuring reflex rules, the team was able to introduce mixing with normal pooled plasma directly on the analyser when initial results exceeded predefined thresholds. This removed the need to extract samples, prepare separate dilution steps manually, and reload it for further analysis, reducing the risk of delays or errors, and improving both standardisation and traceability, particularly during time-sensitive investigations.
Essential integration “While many modern analysers have achieved gains in speed and autonomy, laboratory bottlenecks have shifted to data processing and accreditation- related tasks,” says Stephen. “That’s why the integration of the sthemO 201 with data-management tools such as sthemE Manager has become essential.” Stago’s sthemE Manager is a powerful data management solution that enables biomedical scientists to access and review patient results from a centralised database anytime and anywhere. By integrating laboratory, quality control and patient data, it applies advanced expert rules and coagulation algorithms
to support clinical decision-making, promote best practices, and streamline the accreditation process. During the sthemO’s analyser evaluation, users were able to configure the system to collect verification data, reducing the burden of manual documentation and allowing performance tracking to begin from day one. Beyond setup, the data manager supported ongoing monitoring through integration of IQC and EQA datasets. This enabled not only routine quality control, but also the automatic calculation of measurement uncertainty by different calculation methods, allowing it to be configured to the most appropriate approach for the clinical utility of that method – tasks that would otherwise consume considerable time.
In addition to ongoing monitoring, the system demonstrated features that directly support laboratory compliance with ISO 15189. Verification data could
Stephen continued: “This consolidation of data, reporting, and traceability into a single environment represented a significant step toward more efficient quality management.”
Guided performance for workflow continuity Coagulation analysers are often considered to be among the more technically demanding instruments in a pathology laboratory, requiring familiarity with a wide range of test parameters, sample handling nuances, and result interpretation considerations. Often, workforce redeployment,
training rotations, and reliance on cross- cover arrangements mean that staff may not always have sustained exposure to haemostasis platforms, so systems that support rapid familiarisation without compromising safety are becoming increasingly important for teams like Stephen’s. During the evaluation, the
Stago’s sthemE Manager is a powerful data management solution, which allows users to configure the system to collect verification data, reducing the burden of manual documentation and allowing performance tracking.
WWW.PATHOLOGYINPRACTICE.COM SEPTEMBER 2025 19
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84
