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Follow us on twitter: @csjmagazine


COMMENT


CSJ THE CLINICAL SERVICES JOURNAL Editor


Louise Frampton louiseframpton@stepcomms.com


Technical Editor Kate Woodhead Business Manager


Dean Walford deanwalford@stepcomms.com


Sales Executive Holly Goldring hollygoldring@stepcomms.com


Journal Administration


Katy Cockle katycockle@stepcomms.com


Design Steven Dillon Publisher


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Publishing Director Trevor Moon trevormoon@stepcomms.com


THE CLINICAL SERVICES JOURNAL is published in January, February, March, April, May, June, August, September, October and November by Step Communications Ltd, Step House, North Farm Road, Tunbridge Wells, Kent TN2 3DR, UK. Tel: +44 (0)1892 779999 Email: info@clinicalservicesjournal.com Web: www.clinicalservicesjournal.com


A New Year’s toast


As I sat down and pondered how to start my comment for the first edition of 2022, I had just returned to juggling my editorial duties with home schooling my son – an outbreak of COVID-19 among staff and students had forced the closure of his class. Despite the agonies of explaining fronted adverbials to a disinterested ten-year-old, I was relieved at how far we had come. This was not a lockdown and I had booked my third booster vaccination. It made me pause to reflect on the extraordinary work behind one of the greatest medical achievements of our time that contributed to my more sanguine state in the face of a return to the joys of Google Classroom – I knew this would be temporary and there was a very good chance that, even if we caught it, we would be ok. I owed this reassurance to the scientists behind the vaccination programme.


As such, inspiration for my comment


was gifted in the form of the 44th Dimbleby Lecture by Professor Dame Sarah Gilbert, one of the creators of the Oxford-AstraZeneca vaccine, who shone a light on the extraordinary story behind the vaccine’s development – including the highs and lows. The transcript of her speech is a must-read for us all, and a reminder that preparation for the unknown is everything.


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© Step Communications Ltd, 2022 Single copy: £19.00 per issue.


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The Publisher is unable to take any responsibility for views expressed by contributors. Editorial views are not necessarily shared by the journal. Readers are expressly advised that while the contents of this publication are believed to be accurate, correct and complete, no reliance should be placed upon its contents as being applicable to any particular circumstances. This publication is copyright under the Berne Convention and the International Copyright Convention. All rights reserved, apart from any copying under the UK Copyright Act 1956, part 1, section 7. Multiple copies of the contents of the publication without permission is always illegal.


She explained that a large part of the reason the team of researchers were able to move so fast in 2020 was the work that had already been done, both on other vaccines against other diseases, and on planning for ‘Disease X’. “Disease X was a placeholder


representing a future, hypothetical disease. No one knew what it would be, or when it would emerge, but experts agreed that the emergence of something, sometime soon, was inevitable,” she commented. She warned that the pandemic is “not done with us”, however. The spike protein of the new variant, Omicron, contains mutations already known to increase transmissibility. There are also additional changes that may mean antibodies induced by the vaccines, or by infection with other variants, may be less effective at preventing infection with Omicron. “Until we know more, we should be cautious, and take steps to slow down the


JANUARY 2022


spread of this new variant,” she warned, adding that getting vaccinated now, and getting boosted, is still the best way to protect ourselves. However, she also warned that, in the future, there will also be a Disease Y and the next virus could be worse – more contagious, more lethal, or both. “We cannot allow a situation where we have gone through all we have gone through, and then find that the enormous economic losses we have sustained mean that there is still no funding for pandemic preparedness,” she commented. “Just as we invest in armed forces and intelligence and diplomacy to defend against wars, we must invest in people, research and manufacturing, systems and institutions to defend against pandemics,” she concluded.


Until we know more, we should be cautious, and take steps to slow down the spread of this new variant


While we must continue to prepare for future threats, 2021 will pass into history, as the year that we fought back against ‘Disease X’. Allowing myself to enjoy a small (third) dose of optimism, I plan to raise a glass to Professor Gilbert and her colleagues as the clocks chime midnight…Right now, I have a lesson on fronted adverbials, however… View the transcript at: https://www. ox.ac.uk/news/2021-12-07-professor- dame-sarah-gilbert-delivers-44th- dimbleby-lecture


Louise Frampton l Editor louiseframpton@stepcomms.com


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