MICROSCOPY & IMAGING
THE PROMISE OF IPHOTOACOUSTIC
MAGING
The fl exibility of compact, mobile, photoacoustic imaging equipment on wheels is helping to advance groundbreaking medical research, diagnostics and treatment
reclinical laboratories at academic facilities and contract research organisations (CROs) have traditionally relied on fi ve main imaging modalities: optical, acoustic, x-ray, MRI and nuclear. Now, photoacoustic imaging, which combines optical and acoustic modalities, is enabling some of the most promising medical research today including providing images of biological structures for increased visibility during surgery and facilitating the analysis of plaque
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composition to better diagnose and treat coronary artery disease (CAD). With photoacoustic medical imaging, nanosecond lasers deliver light pulses to specifi c biological tissues. T e laser’s energy is absorbed and converted into heat, which generates an ultrasonic (sound) wave that can be detected by a transducer and processed to form an image. Due to the varied response of components in biological tissue based on user defi ned laser parameters, images can include information about the function of examined tissues as well.
However, despite its promise,
preclinical researchers were limited to using large, fi xed benchtop systems mounted to immovable laser tables. Now, compact, mobile photoacoustic platforms are available and ready for use in preclinical and clinical environments, including commercial hospital settings. Like an ultrasound machine, mobile photoacoustic systems could be
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