TABLETING
2100 banding machine from Syntegon, visitors to this year’s Interpack were able to experience two essential process systems for solid dosage forms with optimised functionalities. T e Sepion series with drum sizes from 175 to 1,000 litres was presented for the fi rst time at the virtual Interpack 2020. T e versatile system for the fi lm and sugar coating of tablets comes with Syntegon’s latest human machine interface (HMI), an intuitive and modern solution for even easier process control and monitoring. In addition, the coater ensures signifi cantly shorter process times thanks to increased spray rates as well as recipe-controlled, enhanced cleaning. With the GKB 2100 banding machine, Syntegon is responding to the growing demand for oncological therapeutics, phytopharmaceuticals and dietary supplements, as well as the trend towards vegan alternatives made from HPMC or pullulan. In addition to gentle handling, the GKB 2100 provides reliable sealing and drying, thus ensuring high tightness levels.
W
MODERN COATER WITH INTUITIVE CONTROLS T e new HMI is the digital control and monitoring centrepiece of various systems in the fi rm’s machine portfolio. T is is also the case with the Sepion 175 drum coater: from setup and recipe creation to process monitoring and reporting, the interface supports operators in each process step. For example, the HMI allows to easily initiate sampling during the coating process. T e distance between the spray nozzles and the tablet bed can also be specifi ed in the recipe; the spray arm adjusts automatically. T e coater even enables tracking of the spraying arm via optional laser distance measurement. “With the Sepion 175, we are specifi cally targeting customers who need a fl exible and effi cient coating solution for small batch sizes,” says Fritz-Martin Scholz at Syntegon. “T e Sepion coater meets both requirements thanks to its modern control system and innovative drum design.” T e interface also provides easy access to the company’s digital service
48
www.scientistlive.com
ith the Sepion 175 drum coater and the GKB
The HMI supports operators in each process step
SOLID DOSAGE SOLUTION
solutions – paving the way for greater overall equipment eff ectiveness: detailed information on essential OEE data, machine settings and alerts enables operators to plan preventive maintenance and thus reduce downtime. In terms of end-to-end optimisation,
the core technological components of the Sepion 175 also off er coating benefi ts. A higher number of spray nozzles combined with an extended drum length results in a spray rate that is up to 40% higher than some comparable established coaters. “As a result, the process times for fi lm coating turn out to be shorter overall; however, the yield and quality of the coating remain unchanged at a high level,” says Scholz.
OPTIMISED CLEANING TIMES In terms of cleaning technology, Syntegon has made important changes based on comprehensive tests, leading to signifi cant savings compared with benchmark coaters. “Operators can individually optimise the cleaning process via a fl exible cleaning recipe. T is enables manufacturing companies to use their cleaning agents and resources as eff ectively as possible,” explains Scholz. T e coater
Optimised tools for the coating and sealing of solid dosage forms
thus contributes to more effi cient and sustainable processes. A validated, reproducible recipe forms the basis for the entire cleaning process and minimises manual operator intervention.
INNOVATIVE SEALING OF HARD CAPSULES Visitors to the show were also able to experience the new GKB 2100 banding machine for sealing hard gelatin and cellulose-based capsules at an output of up to 125,000 pieces per hour. “T e liquid-fi lled capsules of both materials require additional sealing, known as banding, to seal them tightly,” explains Matthias Mössinger, senior market expert Pharma Solid at Syntegon. T e gentle handling of the capsules poses another challenge. To avoid crushing during feeding into the sealing area, the company relies on an automatic and extremely gentle roller feed system. Sealing rollers apply the sealing liquid in two layers in two independently controlled stations before capsules enter the drying module in up to 12 tracks. In this area, the applied band dries in segmented zones by means of conditioned air.
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60
