4 HPLC flowmeter approved by leading institute
Testa Analytical reports, after extensive testing, that its high-precision HPLC flowmeter has been approved by one of the most prestigious metrology Institutes in Beijing, China.
Scientists at this pioneering national statutory authority in the field of metrology, investigated the HPLC flowmeter as a modern alternative to the traditional Flow calibration method for HPLC pumps (National Metrology Verification Regulations of the People’s Republic of China JJG705-2014 Liquid Chromatography).
This method, based on gravimetric determination of average flow, requires around 60 minutes to complete the calibration process. Scientists at the Metrology Institute have confirmed that the Testa Analytical HPLC flowmeter has proved to deliver precise flow rate within one second, and these test results are consistent with the traditional gravimetric method.
A scientist from the Metrology Institute said “The Testa HPLC flowmeter is simple to install and use, is compact and convenient, and provides consistently reliable quantitative and fault diagnostic data. Usefully the flow measurement data is read directly by the device software without need for any calculations. Overall, we feel that this revolutionary product will save HPLC system users considerable time they have previously spent on undertaking calibrations.”
The HPLC flowmeter range from Testa Analytical sets the benchmark for continuous non-invasive monitoring of the performance of pumps serving HPLC and UHPLC systems. Compatible with all common solvents, the compact HPLC flowmeter powers itself from a USB connection. At the heart of the HPLC flowmeter is a high-resolution thermal flow sensor that is both extremely accurate and sensitive. This non-invasive sensor enables the device to operate over a wide dynamic range. Each Testa flowmeter is supplied with an easy-to-use PC based App that allows users to continuously record, and store measured flow rate data from a HPLC system. Current flow rate is displayed on the devices integral high-resolution OLED display.
More information online:
ilmt.co/PL/XNn3 62782pr@reply-direct.com New IC system elevates lab capabilities
Thermo Fisher Scientific Inc has unveiled the Thermo Scientific™ Dionex™ Inuvion™ Ion Chromatography (IC) system, a cutting-edge instrument designed to simplify and enhance ion analysis for laboratories of all sizes. With a focus on reliability, efficiency, and adaptability, this new IC system caters to the diverse analytical needs of researchers working with ionic and small polar compounds.
In response to the increasing emphasis on environmental safety, particularly concerning food and water supplies, Thermo Fisher aims to provide versatile and sensitive instruments for comprehensive testing and analysis. The Dionex Inuvion IC system is aligned with the company’s mission to contribute to a healthier, cleaner, and safer world. It equips environmental, industrial, municipal water, and food and beverage labs with the essential tools to detect ionic contaminants in water and identify corrosive substances in oil and gas. Additionally, the system ensures quality assurance and control of small ionic compounds in food, beverages, and pharmaceuticals.
The Dionex Inuvion IC system is engineered to streamline lab operations by offering easily configurable workflows and a compact footprint. Its flexibility allows customisation to meet current analytical requirements while enabling the extension of IC capabilities to adapt to changing sample types and workflow needs in the future, ensuring a cost-effective and efficient solution.
Lidija Raicevic, Vice President and General Manager of Ion Chromatography and Sample Preparation at Thermo Fisher Scientific, stated: “As the originator of ion chromatography, we continue to lead innovation in all areas of instrumentation and column chemistry to meet our customers’ growing needs for better resolution, faster results, and intuitive lab experience. The Dionex Inuvion system is built on years of expertise and will provide enhanced capabilities to labs of all sizes while helping streamline our IC portfolio.”
Key features of the Dionex Inuvion IC system include advanced pump technology that enhances speed, quality, and reproducibility; operator-friendly engineering to improve the user experience; and user-installable accessories to extend capabilities and achieve the highest quality results.
More information online:
ilmt.co/PL/pKVy 62117pr@reply-direct.com New HPLC system enhances biopharma QC efficiency
Waters has introduced the Alliance iS Bio HPLC System, a revolutionary solution tailored to address the unique operational and analytical hurdles encountered by biopharma quality control (QC) labs. Engineered to optimise efficiency, ensure compliance, and accelerate product delivery, this system is poised to meet the stringent requirements of the biopharma industry.
With a focus on enhancing productivity, the Alliance iS Bio HPLC System targets common errors, aiming to eliminate up to 40% of these occurrences. By minimising the time spent on investigating failed runs and out-of-specification results, QC analysts can streamline their workflow and expedite sample analysis.
Featuring a bio-inert design in critical internal components, including the system flow path, this innovative solution mitigates unwanted interactions from metal-adsorbing analytes. This safeguard ensures the integrity of the analysis, providing reliable and accurate results.
The system offers the flexibility to leverage platform methods with confidence, reducing the need for extensive column conditioning and method development. This capability not only saves time but also enhances the efficiency of the QC process.
Complementing the Alliance iS Bio HPLC System is the integration with Waters Empower Chromatography Software. This seamless collaboration facilitates data collection, management, and reporting of chromatography test results. Compatible with both Waters and third-party liquid chromatography instruments, this integration empowers high-volume QC labs to efficiently manage operational risks, overcome disruptions, and optimise overall productivity.
More information online:
ilmt.co/PL/7nv1 62639pr@reply-direct.com Improving precision in nanoparticulate formulation dispensing
Biotech Fluidics has successfully developed and implemented an innovative combined micro flowmeter and degasser system to improve the dispensing of a nanoparticulate formulation for a leading medical technology company.
To ensure precise spray coating of the pharmaceutical formulation onto a medical device, the contract manufacturing organisation (CMO) enlisted Biotech Fluidics for their expertise in turnkey fluidics systems and degassing solutions.
Biotech Fluidics’ Micro Flow Meter, optimised for flow rates ranging from 100 nl to 80 µL/min with a high resolution of 1 nl/min, proved to be the ideal tool for monitoring the accuracy and consistency of low-volume liquid dispensing.
Robin Oz, Project Manager at Biotech Fluidics, explained: “While flowmeters are available for lab-scale processes, they often fall short in monitoring micro and nanoscale liquid volumes. Our Micro Flow Meter, a non-invasive device offering real-time flow data, was perfect for ensuring the precision of the pharmaceutical spray coating. Although our flowmeter is calibrated for aqueous solutions, we collaborated with our customer to develop a robust calibration for acetone, the solvent used in the manufacturing process.”
Dr Oz added: “Microbubble formation, which compromised dosing precision, was a challenge we addressed by integrating a high-performance degasser into the process line. Our DEGASi® Plus Nano inline degasser, with an internal volume of just 25 µl and optimised for fluid flows up to 100 µL/min, effectively resolved this issue.”
He concluded: “After demonstrating the reliable operation and monitoring accuracy of the micro flowmeter and degasser setup, our client has placed an order for 32 systems.” More information online:
ilmt.co/PL/OkWM and
ilmt.co/PL/LLlR
62853pr@reply-direct.com
LAB ASIA - AUGUST 2024
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