16 Ultrasonic cleaning solutions for laboratory applications


The cavitation phenomenon consists of the formation and growth of millions of microscopic bubbles under a low-pressure stage, produced into the ultrasonic bath due to a high power transducer 40kHz. These bubbles break in all directions and attack every surface in contact with water, erasing dirt, impurities and pollutants when contacting with the materials or pieces into the bath. This phenomenon allows cleaning all kind of items without the need of disassembling, due to all the surfaces being in contact with the liquid. The heating function of the unit allows the acceleration of this cleaning process.


Wiggens presents two series of standard ultrasonic cleaners with reliable quality and useful features, which allows the users a wide range of cleaning applications such as lab materials, medical instruments, dental prosthesis, optics, industrial items, jewelleries, also the degasification or liquid dissolution and compact substances disaggregation.


The following are the standard working volumes supplied: 3, 6, 10 and 22 litres, and bespoke volumes can be ordered for different applications. All functions can be viewed and monitored on a large and clear touch screen display. The parameters can be set by screen touching, including the ultrasonic working power (40% to 100%), bath temperature (20°C to 80°C), timer and warning function for safety.


All models are equipped with lids and trays that allow the parts they introduce to be directly cleaned without damaging the transducers and for easy handling.


In addition to the standard ultrasonic cleaners, Wiggens also offers the ultrasonic cleaners with special added functions. The Shaking Ultrasonic Cleaner is a good example, which means that the sample can be pre-homogenised at a specific shaking speed, and then final homogenisation can be achieved in a very short time, using ultrasonic power These two procedures can be carried out simultaneously or separately. Another added function is an ultrasonic cleaner with cooling for use in pathology and analysis labs, where the temperature of bath can be maintained at 10°C to 40°C even with the ultrasonic power generating heat continuously.


Contact Wiggens to accelerate your cleaning process. More information online: ilmt.co/PL/9D59


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GLP-1R reporter cell line advances diabetes and obesity research


AMSBIO has introduced a new Glucagon-Like Peptide 1 Receptor (GLP-1R) reporter cell line, designed to advance research in diabetes and obesity. GLP-1R plays a crucial role in blood sugar regulation by enhancing glucose-stimulated insulin secretion, making it a key target for type 2 diabetes treatments. The regulation of the GLP-1R signalling pathway has led to the development of several FDA-approved GLP-1 agonists. Additionally, GLP-1R agonists aid in weight management, reduce cardiovascular disease risk, and protect pancreatic beta cells.


The new GLP-1R/CRE Luciferase Reporter HEK293 cell line measures luciferase activity to monitor GLP-1R activation in cells. This cell line is ideal for cell-based binding assays and screening human GLP-1R agonists. Its functionality has been validated in dose-response assays with both peptide and small molecule agonists.


AMSBIO has also launched gastric inhibitory polypeptide receptor (GIPR) and glucagon receptor (GCGR) reporter cell lines to complement the GLP-1R cell line. These receptors are vital for blood sugar regulation, and dual agonists targeting GIPR/GCGR and GLP-1R show promise for type 2 diabetes and obesity treatments. Together, these cell lines offer a robust platform for screening combination therapies by measuring the activity of co-stimulatory targets in response to agonists.


To assist investigations into muscle loss caused by GLP-1R agonists, AMSBIO also offers a range of skeletal muscle research products. More information online: ilmt.co/PL/yw4b and ilmt.co/PL/05G0 62905pr@reply-direct.com


Autoclave innovation helps cut water usage by up to 80%


Many countries around the globe have seen their water charges rise, with prices varying greatly by location. In some countries prices are set to rise by as much as 18% over two years. England’s ’Plan for Water’ policy paper states that England and Wales currently use 14 billion litres of water per day and will need an additional 4 billion litres per day by 2050. The success of ensuring every nation’s future public water supply will depend upon a twin-track approach: delivering new supplies of water; and reducing water demand. To reduce demand, we all need to use water sensibly and use more water efficient resources. Priorclave stand ready to assist you and your organisation in this endeavour.


When the University of Alabama at Birmingham in the United States of America compared their steam-jacketed autoclaves and Priorclave’s non-jacketed laboratory autoclaves side by side, they found that jacketed autoclaves used in excess of thirty times more water – with no corresponding benefit. In field tests, Priorclave laboratory autoclaves operating costs have been documented at more than 80% lower than same-capacity jacketed autoclaves.


Shape can have a significant impact on performance, given two like-sized autoclave chambers, you’ll find that the rectangular chamber requires a heater rated at roughly three times that of a comparable cylindrical chamber. In practice, it takes about as much energy just to heat a rectangular chamber up to begin sterilisation as it does to run an entire cycle through a cylindrical model. On an annual basis, a cylindrical-vessel front-loading Priorclave autoclave can be expected to use 1/6th to 1/10th as much water and energy as a comparable rectangular model.


To discover how much you could save, contact the Priorclave sales team. More information online: ilmt.co/PL/jMLO


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Preserving sample integrity in genetic testing workflows Featuring a novel dual-cap design with both hinged lid and screw cap, Azenta Life Sciences Cap2


™ PCR microcentrifuge tube is perfect for preserving


the integrity of samples used in genetic testing workflows. Acting as both a collection and processing 0.2ml tube, sample transfer is minimised making for greater efficiency and less wastage.


Proven to ensure sample traceability in wide ranging genetic testing workflows, including pre-implantation genetic testing (PGT) – each Cap2


a unique 2D datamatrix code as well as a numerical human readable identifier to prevent sample tracking errors. All Azenta tubes, including the Cap2


systems from Azenta and all other industry-recognised manufacturers.


Manufactured from high quality virgin polypropylene, in a class 8 clean room environment, each batch of tubes is tested to certify them endotoxin and DNase/RNase free as well as containing no detectable leachables or extractables. Vital considerations for sample collection tubes used in genetic testing workflows.


More information online: ilmt.co/PL/A5qk 62788pr@reply-direct.com tube has , perform without compromise in conjunction with automated code reading, capping and sample management


LAB ASIA - AUGUST 2024


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