Chromatography 15 The Advantages of Coupling GCxGC with QTOF Detection in MS/MS Mode
An application note from JSB studies the feasibility of coupling GCxGC with QTOF detection in MS/MS mode.
GC-QTOF is a valuable technique for challenging applications that demand confident identification in highly complex matrices, such as, metabolomics and pesticides analysis. Comprehensive two- dimensional gas chromatography (GC×GC) is the chromatographic method of choice to unravel high sample complexity. Compared to classic GC, GC×GC grants superior separation power and unmatched peak capacity by coupling two different separation mechanism in a single analysis.
The results of the study show the practicality of operating the QTOF in MS/MS mode also coupled to GCxGC. This feature can be a powerful profiling tool to complement two-dimensional chromatograms and HRMS and their excellent selectivity in order to achieve even more confident identification and determine more structures of unknowns.
The study concluded that by using the Agilent 7250 QTOF detector, high-resolution, accurate mass, soft ionisation and MS/MS capability was ensured. These features are generally used in GC-QTOF for advanced identity confirmation and structure elucidation. It was possible to use GC×GC with the QTOF in MS/MS mode, and by careful optimisation, good MS/MS data, also for the sharp modulated peaks, was obtained. This technique can be a very powerful tool for the identification of targets and unknowns with enhanced confidence and selectivity.
More information online:
ilmt.co/PL/v0Jm and
ilmt.co/PL/AREZ 49791pr@reply-direct.com
The Use of Gas Chromatography to Test for Traces of Explosives
Chromatography can be an extremely valuable tool in the detection of explosives. Following an explosion, it is crucial to a police investigation to identify if an explosive was used, and if so what type. Finding traces of explosives on a suspects clothing or belongings can link that suspect to a case. Once trace samples are collected, the amount of explosives in the sample can be on the low nanogram range.
TEA detectors, coupled with GC are widely used for the forensic analysis of trace explosives. Its simple operation, very high sensitivity and very high selectivity for nitroso compounds, makes the TEA a superior choice of detector for this application.
The Ellutia 800 series TEA is already being used in the world class Dubai Police science and criminology laboratory, and a detailed case study can be found on Ellutia’s website.
More information online:
ilmt.co/PL/pZ9v 48648pr@reply-direct.com New E-Commerce Website Launch Announced
Chromatography columns and media supplier, ES Industries Inc, announces the launch of new website to ease online shopping of products for its global prospects.
ES Industries Inc launched its ecommerce website with the aim of providing its worldwide customers with premium quality chromatography products at affordable factory direct prices with economical worldwide shipping.
The launch of the ecommerce website by ES Industries underlines the company’s desire to serve its thousands of customers scattered across the over 200 countries it serves, ensuring they shop easily and safely.
ES Industries Inc offers a wide variety of chromatography products for difficult separations and purifications in different categories, available in bulk or packed columns, including analytical high performance liquid chromatography (HPLC), preparative HPLC, chiral chromatography and super critical fluid chromatography (SFC).
The ES Industries site is easy to navigate, ensuring anyone and everyone can easily locate their favourite products with the least stress.
ES Industries allows Paypal and credit payment methods, allowing anyone to shop for their favourite chromatography items without the fear of their financial details being compromised. Other features shoppers enjoy from the launch of the website include protective shipping with product declaration, friendly helpful and professional customer services.
More information online:
https://esind.com/
50005pr@reply-direct.com
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