LABORATORY PRODUCTS


Autoclaves Material selection in autoclave design: Why 316 stainless steel endures


Subjected to repeated cycles of extreme temperature, pressure, and humidity, material selection is not simply a design preference but a critical determinant of an autoclave’s long-term performance and total cost of ownership.


Not all stainless steels are created equal, and 316 stainless steel distinguishes itself through the addition of molybdenum to its alloy composition. This element significantly enhances resistance to pitting and crevice corrosion, which can otherwise occur in wet, chloride-rich environments. For this reason, laboratories and facilities seeking robust, reliable, and long-lasting sterilisation solutions should regard 316 stainless steel as a fundamental requirement.


Priorclave is one of the few autoclave manufacturers globally to retain complete control over its entire supply chain. This approach ensures the use of 316 stainless steel in every autoclave it produces, with all principal components, including pressure vessels, being fabricated in-house at Priorclave’s South East London facility.


Priorclave’s most popular autoclave is the EV100 BASE, a compact unit occupying less than one cubic metre while offering an impressive 100-litre chamber capacity. Its top-loading, vertically aligned cylindrical chamber enables it to accommodate even the tallest laboratory vessels, making it particularly popular in research environments.


The EH150 SMART remains one of Priorclave’s most widely adopted front- loading autoclaves. Vacuum-equipped for porous loads, it combines an ergonomic loading height with low power and water consumption.


For high-throughput applications, the SH450 RSC PERFORMANCE delivers rapid cycle times. Both steam-jacketed and vacuum-equipped, it is designed to handle demanding loads with ease while producing drier, cooler loads more quickly.


With robust 316 stainless steel construction, proven reliability, and consistent performance, Priorclave’s BASE, SMART, and PERFORMANCE ranges set the benchmark in modern autoclave design.


More information online: ilmt.co/PL/xD1y and ilmt.co/PL/LAXD


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A new benchmark in differential scanning calorimetry


Anton Paar has introduced the Julia DSC series – a next-generation line of differential scanning calorimeters designed for exceptional speed, precision, and ease of use in both research and quality control.


Expanding Anton Paar’s materials characterisation portfolio, the Julia DSC brings differential scanning calorimetry alongside the company’s established strengths in rheometry, particle characterisation, and surface and pore analysis.


“Julia DSC bridges the gap between speed, precision, and simplicity,” explained Product Manager Jiří Kislinger. “Labs can move from setup to results in minutes, with flexible cooling options and intuitive software that make even complex analyses straightforward.”


The system features an air-cooled Peltier module capable of reaching -35°C without external chillers. For lower temperatures, interchangeable cooling units can be swapped in under five minutes to achieve cryogenic conditions down to -170°C – the fastest switching available.


Driven by the intuitive Julia Suite software, users benefit from a graphical method


Calorimetry


AAV reference standards advance gene therapy research


Amsbio has launched a new range of Adeno- Associated Virus (AAV) reference standards to help researchers optimise AAV production and improve the accuracy of gene therapy studies.


editor with smart suggestions, automated calibration, built-in performance checks, and a dedicated QC mode. The platform is designed to deliver results quickly, accurately, and with minimal training.


Throughput can be further increased with an optional autosampler accommodating up to 70 samples and eight references, while an energy-saving eco mode supports more sustainable lab operation.


From routine quality control to advanced R&D, the Julia DSC series makes high- performance calorimetry faster, simpler, and more accessible than ever before.


More information online: ilmt.co/PL/7Wk1 66172pr@reply-direct.com


AAVs are widely used for delivering DNA to target cells without carrying viral genes, making them a safe and versatile tool. However, a major challenge in production is the presence of empty viral capsids - particles that do not contain a gene payload. Even after purification, these empty capsids remain, which can affect experimental reliability and therapeutic outcomes. High-quality reference standards are essential to standardise measurements and ensure consistent, reproducible results.


The new AAV reference standards from Amsbio are thoroughly characterised, providing precise titres and well-defined full-to-empty capsid ratios. These standards are crucial for quantitative AAV production, enabling researchers to calibrate assays, validate testing methods, and maintain consistency across experiments.


Amsbio offers both full and empty capsid reference materials across multiple AAV serotypes. Full AAV standards are used to calibrate qPCR and ELISA assays, establish benchmarks for critical quality attributes, and support consistency from research to clinical


Reagents


applications. Empty AAV standards serve as reference points to quantify the proportion of full versus empty capsids in production batches, aiding quality control, immunogenicity assessment, and regulatory compliance.


Each AAV reference standard undergoes extensive characterisation, including ddPCR, ELISA, silver staining, and mass photometry, along with full safety testing for bioburden, mycoplasma, and endotoxin. Quantification data are traceable to ATCC Reference Standard Material, giving researchers confidence and consistency in gene therapy development, quality control, and regulatory workflows.


More information online: ilmt.co/PL/9OjR 66503pr@reply-direct.com


Reagents Sharper, brighter dyes for spatial imaging


Biotium has expanded its Tyramide Signal Amplification (TSA) portfolio with TyraMax™ Amplification Dyes and Kits, designed for superior brightness, photostability, and buffer stability. The dyes deliver up to 100-fold higher detection sensitivity compared to conventional immunofluorescence, making them ideal for multiplex fluorescence and advanced spatial biology workflows, including tissue mapping and cyclic immunofluorescence (CycIF).


The TyraMax™ line offers the widest range of colours, from blue to near-infrared, allowing researchers to design complex multiplex panels with maximum flexibility. All dyes, including near-IR options, remain stable in amplification buffer for at least 24 hours, supporting automated staining workflows and reducing the risk of signal loss due to oxidation.


“Many spatial biology methods still rely on dyes that underperform in brightness or stability,” said Lori Roberts, PhD, Director of Bioscience at Biotium. “TyraMax™ dyes address these limitations, enabling scientists to build larger, more reliable multiplex panels for cutting-edge imaging applications.”


TyraMax™ dyes are available as standalone reagents, trial sizes, or ready-to-use multiplex sets such as 3-Plex and 5-Plex Amplification Dye Sets with DAPI. Compared to leading competitors, TyraMax™ provides brighter, more stable signals at a more accessible price point, giving researchers confidence to optimise complex panels and workflows.


With TyraMax™, Biotium empowers scientists to achieve higher sensitivity, sharper signals, and more consistent results in spatial biology, tissue mapping, and multiplex fluorescence imaging. The dyes and kits are available through Biotium and authorised distributors worldwide.


More information online: ilmt.co/PL/vlRd 66607pr@reply-direct.com


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