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CONNECTING SCIENCE, BRIDGING INNOVATION


High-throughput UV and fl uorescence quantifi cation


workstations. Integrating the eviDense UV Photometer and eviFluor Duo fl uorometer directly onto the deck, laboratories can measure nucleic acid concentration and purity (260/280 and 260/230 nm) and perform fl uorometric assays without manual intervention.


Beckman Coulter Life Sciences has introduced fully automated UV and fl uorescence-based nucleic acid quantifi cation on its Biomek i-Series


The system combines liquid handling automation with real-time absorbance and fl uorescence detection, enabling researchers to quantify nucleic acids from purifi ed or complex samples with minimal sample loss. Non-destructive analysis allows immediate downstream processing or recovery, while fl uorometric measurements of 96 samples can be completed in just 20 minutes.


This integration streamlines workfl ows


DNA/RNA Quantifi cation


for NGS library preparation, extraction, and other molecular biology applications, reducing hands-on time and eliminating variability associated with manual pipetting and measurement. Both UV and fl uorescence detection operate seamlessly within the automated platform, supporting reproducible, high-quality data for genomics, drug discovery, and research laboratories.


By merging high-precision optics with automated liquid handling, Beckman Coulter is helping labs increase throughput, reliability, and workfl ow effi ciency - all while ensuring sample integrity and measurement consistency.


More information online: ilmt.co/PL/0KZV 66615pr@reply-direct.com


Novel therapy gains FDA clearance for ALS clinical trial


Neurizon Therapeutics Ltd has received FDA clearance for its lead candidate, NUZ-001, to enter the HEALEY ALS Platform Trial as Regimen I. This approval allows the company to begin site activations, obtain single IRB approvals, and prepare for patient enrolment, expected to start in early 2026.


The HEALEY ALS Platform Trial is a multicentre, adaptive study designed to accelerate the evaluation of potential ALS therapies. By testing multiple investigational drugs simultaneously, the trial streamlines operations and improves effi ciency across sites.


NUZ-001 targets key pathological features of ALS, including TDP-43 aggregation and impaired autophagy, and has shown promising oral bioavailability, CNS penetration, and a favourable safety profi le in preclinical studies. FDA clearance of the protocol represents a critical milestone for Neurizon as it advances its development program toward potentially disease- modifying therapies for ALS.


Dr Michael Thurn, CEO of Neurizon, said: “This FDA clearance is an important step forward in bringing NUZ-001 to patients living with ALS. The HEALEY ALS Platform Trial


Clinical Trials


provides an effi cient, collaborative framework to test new treatments, and we look forward to beginning patient enrolment in 2026.”


Professor Merit Cudkowicz, Principal Investigator of the HEALEY ALS Platform Trial, added: “We are excited to welcome NUZ-001 to the platform trial. The FDA’s clearance allows us to move swiftly to start sites and begin enrolment, bringing us closer to identifying new therapies for ALS.”


More information online: ilmt.co/PL/1nQE 66378pr@reply-direct.com


Autoclave sets new standards in liquid load sterilisation


Laboratories working with culture media and aqueous solutions can now benefi t from enhanced performance and safety with the introduction of the Labclave-L autoclave, from LTE Scientifi c, engineered to meet the precise demands of media sterilisation.


Developed to meet the needs of laboratories handling sensitive liquid loads in bottles, fl asks, or tubes, the Labclave-L combines advanced functionality with user-friendly design. At the heart of its innovation is integrated air ballast technology, which enables stable, pressure-controlled cooling to safeguard media and reduce cycle times.


Sterilising liquids poses well-known challenges, particularly when working with sealed or partially sealed containers. Rapid pressure drops during cooling can lead to fl ash boiling, media loss, or even glassware breakage. The Labclave-L tackles these issues by introducing controlled compressed air into the chamber during the critical cooling phase. This maintains internal pressure, allowing a gentler return to ambient conditions and minimising the risks commonly associated with liquid load sterilisation. Benefi ts of air ballast technology include preventing sudden pressure drops and fl ash boiling, maintaining container integrity, preserving


Autoclaves


to the load. The Labclave-L’s pressure- controlled cooling reduces reliance on lengthy cycles, resulting in quicker turnaround, lower energy consumption, and a safer working environment for lab personnel. Key operational advantages include shorter cycle times and increased throughput, energy-effi cient sterilisation cycles, and safer handling with reduced spillage or breakage risks.


Ideal for laboratories sterilising nutrient broths, agar media, buffer solutions, and other aqueous materials, the Labclave-L is designed to streamline the sterilisation process without compromising quality. With robust construction and intuitive controls, it delivers the repeatability and reliability needed in fast-paced laboratory settings.


the volume and consistency of media, and supporting faster, more predictable cycle completion.


Traditional autoclaves without air ballast often require longer cooling times or additional manual checks to avoid damage


The Labclave-L represents a signifi cant step forward in autoclave technology for media sterilisation. By combining safety-focused design with performance-enhancing features like air ballast technology, it provides a dependable solution for laboratories looking to optimise liquid load processing while safeguarding both product and personnel.


More information online: ilmt.co/PL/8e9B 66567pr@reply-direct.com


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At the National Trust’s Plant Conservation Centre (PCC), protecting the UK’s rare and endangered plants requires a blend of expertise, precision, and the right technology. To ensure the survival of some of the nation’s most fragile species, staff are now using a Monmouth Scientifi c Class 2 Biological Safety Cabinet. This specialised equipment allows delicate plant tissues to be propagated in completely sterile conditions, safeguarding both the plants and the people caring for them.


Propagation at the PCC is both art and science. Working with species on the edge of extinction means every step must be carefully controlled. Techniques such as tissue culture and grafting, where buds, meristems, or leaf sections are grown under laboratory conditions, are highly sensitive to contamination. Even minor errors can compromise weeks or months of painstaking work, making the environment in which these plants are handled just as important as the expertise of the staff.


The Class 2 cabinet provides a controlled workspace that protects plant material, personnel, and the wider environment simultaneously. Inward airfl ow ensures staff are shielded from exposure to biological material, while sterile laminar airfl ow prevents contamination of sensitive samples. Exhaust air is fi ltered, maintaining the safety and integrity of the laboratory. Integrated into the PCC’s rigorous biosecurity protocols, the cabinet underpins key conservation practices, from quarantining newly acquired specimens to enhancing hygiene across all laboratory processes.


Since its installation, the PCC has seen measurable improvements. Propagation rates have increased thanks to reduced contamination, while staff can work with confi dence knowing their safety is assured. Repeatable workfl ows have boosted effi ciency, allowing the centre to accelerate conservation efforts and focus on critical projects such as maintaining seed and tissue banks, supporting species reintroduction, and collaborating with universities and research institutes.


“The Monmouth Scientifi c Class 2 is now fundamental to our work,” says Chris Trimmer, PCC Manager. “It allows us to carry out delicate propagation safely and effi ciently, and the team at Monmouth Scientifi c were fantastic in supporting the installation and integration.”


By combining horticultural expertise with advanced laboratory technology, the PCC and Monmouth Scientifi c are creating a sterile haven where some of the UK’s rarest plants can thrive. From laboratory benches to rewilded landscapes, each successfully propagated specimen represents a vital step in protecting the country’s botanical heritage for future generations.


More information online: ilmt.co/PL/32QN 66158pr@reply-direct.com


Safety Cabinets


Class 2 BSC drives success in plant conservation


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INTERNATIONAL LABMATE - FEBRUARY 2026


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