Chromatography 7 Inert HPLC columns enhance biotherapeutic analysis
A new range of inert HPLC columns from Agilent is helping biopharma researchers achieve sharper separations and higher sensitivity in peptide and oligonucleotide analysis. The Altura line – designed for applications such as GLP-1 and oligonucleotide drug development – combines advanced inert surface technology with exceptional reproducibility and reliability.
Developed to meet the growing demands of biotherapeutic R&D and QC, Altura columns deliver faster conditioning, improved peak shape, and enhanced detection sensitivity. When paired with Agilent’s 1290 Infi nity III Bio LC, the system achieves up to 30 times higher peak areas compared to conventional columns.
By minimising analyte-surface interactions and ensuring consistent performance across challenging biomolecules, the Altura range enables reliable impurity profi ling and more effi cient method development. Independent studies report up to 30% higher sensitivity and reduced peak tailing for acidic peptides.
The Altura HPLC family adds to Agilent’s expanding portfolio of inert fl ow-path solutions, supporting precise and reproducible separations for the next generation of complex biotherapeutics.
More information online:
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Minimising sample loss with low-reactivity uncoated autosampler vials
In high-precision analytical workfl ows, even the vial can infl uence your results. Microsolv’s RSA™ (Reduced Surface Activity) Autosampler Vials are uniquely engineered to eliminate a common source of variability - surface interactions - without relying on coatings. By starting with a cleaner, more inert glass surface, RSA™ vials help ensure your samples stay true from injection to analysis.
Unlike coated vials that rely on surface treatments to reduce reactivity, RSA™ vials are completely uncoated. Instead, they are manufactured using a proprietary process that inherently reduces surface activity in the glass itself. This eliminates the need for coatings, which can degrade over time or introduce unwanted variables into sensitive analyses.
By minimising reactive sites such as silanols, RSA™ vials provide a more stable and inert environment for your samples. This is especially critical when working with low-concentration or adsorption-prone compounds like peptides, proteins, and basic drugs.
Designed for universal compatibility with all major autosamplers, RSA™ vials are a practical upgrade for laboratories aiming to improve reproducibility and reduce variability. Whether you’re conducting pharmaceutical, environmental, or clinical research, these uncoated vials offer a dependable solution for high-performance workfl ows.
Explore how RSA™ vials can help reduce variability and improve your chromatography results: More information online:
ilmt.co/PL/m6Wm and
lilmt.co/PL/B2mR
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New buyer’s guide helps universities bring GC into teaching and research
ABV, Flavour,VDKs Test them all in your own brewery
Timetables are tight, and access to instruments is scarce. If you run a teaching lab or a small research group and want to expand your GC capability without breaking your budget, the new Gas Chromatography for Teaching & Research - 200 Series Buyer’s Guide shows how to put a compact GC on the bench and use it well from day one.
The guide keeps things simple and practical. It explains GC in plain English and why it matters in both teaching and research. You’ll see where a small, single-channel GC fi ts when you don’t always know what sample is coming next (see the ‘How to use this guide’ section).
You get the essentials you need to make a decision:
What to buy and why: detectors (FID, ECD, TCD), direct injection vs headspace, and a clear, helium-free carrier gas overview so you can run hydrogen or nitrogen with confi dence
• What you could teach now: six short, 90-120 minute experiments - solvent ID and quant, method variables, LOD/LOQ, reaction monitoring, a forensic ‘unknown’, and %ABV in beer - built for large cohorts
• How to run research without queues: add small GC capacity to cut bottlenecks and give more students hands-on time
• Software choices: full Ellution or Ellution Lite for straightforward teaching and data capture
• Complete education packages: instrument, columns, gases/plumbing, consumables, lesson packs, installation, and training in one bundle
• Prep checklist: space, power, gas, PC - so the GC is ready to run on delivery
If you need proof it works in real labs, you’ll also fi nd comments from UK academics who’ve put compact GC in front of students and kept it reliable. Download the guide now.
More information online:
ilmt.co/PL/b8D0 66012pr@reply-direct.com
Download the Buyer’s Guide
https://bit.ly/gc-brewer
Learn about Finance Options
https://bit.ly/200_Brewer
Sign up for a FreeWorkshop
https://bit.ly/Brewer_work
Ready to get started? Grab the Brewing Buyer’s Guide, join a free workshop, or check out our finance options.
The 200 Series GC helps brewers get fast, reliable answers where they matter
most.Confirm ABV for label compliance, track flavour to keep your flagship beer consistent, and check diacetyl so you don’t risk releasing a buttery batch.
Chromatography Solutions
The Ellutia 200 Series Gas Chromatograph gives brewers fast, reliable results on ABV, flavour, and diacetyl. Small enough for your bench, simple enough for your team.
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