2 August / September 2019 Foreword
Welcome to the third edition of Chromatography Today in 2019. With this issue I would like to introduce the newest member of the editorial review board - Dr Martina Catani. Martina is currently a Research Associate at the University of Ferrara, Italy. She received her PhD in Chemical Sciences from the same University in 2018. She was a visiting PhD student at the Vrije Universiteit Brussel (Belgium) under the supervision of Professor Gert Desmet and at the University of Pécs (Hungary) in the group of Professor Attila Felinger.
Her research activity is mainly focused on the study of mass transfer phenomena and thermodynamic properties of a new generation of chiral stationary phases for high efficiency, ultrafast enantioseparations. Recently, she has also started working on the purification of therapeutic peptides by means of preparative liquid chromatography. In 2019 she spent three months at ETH Zurich (Switzerland) in the group of Professor Massimo Morbidelli working on continuous chromatography techniques. She is the author of 25 papers in peer reviewed journals.
Martina received the Csaba Horváth Young Scientist Award at HPLC2018 in Washington, the Best Poster Award by Agilent Technologies at HPLC2017 in Prague, the Best Oral Presentation Award at the national meeting Merck Young Chemists Symposium in 2017 and the PhD Thesis Award from the University of Ferrara in 2018.
The focus areas within the two themes of Fundamental Aspects of Chromatography and Modern Chromatography Applications for this edition are ‘Supercritical Fluid Chromatography–Mass Spectrometry (SFC-MS)’ and ‘Doping analysis (sports and horse racing)’ respectively. These two themes will be separated by the Knowledgebase.
SFC’s popularity has ebbed and flowed since its first mention at a gas chromatography conference in 1957. Since, the technique has moved from crude packed columns to open tubular columns and now more recently to very high efficiency packed columns. Instrument limitations were historically always cited as being a major hurdle for SFC, and it was difficult to hyphenate SFC with MS, recently however with more instrument companies launching SFC instruments there has been progress in making SFC-MS a mainstream analytical tool.
As with the previous August/September issues this edition will feature prominently at the SFC 2019 conference to be held in Philadelphia, USA. The current issue contains articles which vary from a mini review on the quest for ultra-high performance SFC by Terry Berger, a leader in the field, to one that discusses SFC-MS versus LC-MS and the advantages and challenges of each technique. A walk-up SFC-MS set-up for Fast Purification of reaction Mixtures within a Discovery Chemistry group is discussed by Craig white of Lilly and the HelpDesk covers the considerations when transfer and scaling SFC Methods.
The ‘Doping analysis (sports and horse racing)’ focus area covers the endless chase for success in sports, whether it be a world record or a gold medal the temptation to excel via unethical
Trevor Hopkins - Editor
means continues. Every year 3,000 athletes worldwide test positive for banned substances. Along with track-and-field athletics, body- building, baseball, American football, weightlifting, boxing, wrestling, cycling, ice hockey, rugby, swimming and basketball all have a track record of using performance-enhancing drugs in recent years.
Legally, the World Anti-Doping Agency (WADA) defines doping as ‘any method or substance that enhances performance, that damages health or is contrary to the values of the sport’. However, WADA has no operational role. In theory, every country needs a national anti- doping agency that’s able to independently organise the testing of its athletes. However, in many countries e.g. Russia in the past decade, interference by government and by national sporting federations means that agencies don’t always carry out anti-doping tests. Articles in this issue are provided by the Drug Control Centre, the UK’s Anti- Doping Laboratory on the monitoring of drugs in sport testing and an insight of current trends and recent findings and one by Thermo showing a practical workflow solution for antidoping analysis including steroids in human and equine urine.
The next issue of Chromatography Today will be focusing on Fundamental Aspects Advances in HRMS and the Analysis of large molecules - such as mAbs and oligonucleotides.
Each edition of Chromatography Today is packed with valuable information, however it is impossible to include everything that is submitted. The new revised Chromatography Today website (www.
chromatographytoday.com) is the repository where you will find the other submissions, the latest news from the world of separation science and access to all the historical articles. Perusing the trending news and article sections, it is surprising how much separation science plays a part in daily life without us ever appreciating it, or even realising it. There is a diverse range of areas highlighting just how important separation science is to society with a calendar of events and articles on food, biofuels, medicine, forensics, brewing and environmental clean-up. Please take a look and if you are not a current recipient of the Chromatography Today e-Bulletin - please sign up today.
As always, we welcome article submissions, topic ideas for inclusion in future issues and feedback from our readership. If you have any feedback on this edition of Chromatography Today, please contact us as we are always looking to improve the publication for our readers.
Trevor. Next Issue -
Fundamental Aspects - Advances in HRMS Modern & Practical Applications - Analysis of Large Molecules - mAbs, oligonucleotides/Biomolecule Analysis
To be included call us on +44(0)1727 855574 or
info@chromatographytoday.com
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