Table 2. Included Studies from Low-Middle Income Countries (LMICs)
Author, Year, Country
Aguilar- 2008
Aguilar- 2010
Aiken 2013
Kenya/Low Nascimento Brazil/Middle Nascimento, Brazil/Middle
Interrupted time series
Single hospital Adults (3,343)
Multiple
Ed: Education materials Ex: Policy Ev: Surveillance, data feedback, audit
Before/After Single unit Adults (117)
GI surgery
Ex: Protocols Ev: Surveillance, audits, and data feedback
Design, Setting, Population (No.)
Before/After Single hospital Adults (308)
Surgical Specialty
GI surgery Interventions Ex: ACERTO protocol IPC Measures
ACERTO: preoperative nutritional support if malnourished, early postop feeding, no mechanical bowel preparation, Avoidance of excess IVF, drains & nasogastric tubes, early mobilization
ACERTO: preoperative nutritional support if malnourished, early postop feeding, no mechanical bowel preparation, avoidance of excess IVF, drains and nasogastric tubes, early mobilization
SAP policy
Compliance Increase
SSI Def. SSI Outcome
Not reported Decreased by 66% Pre: 9/78 (11.5%) Post: 9/230 (3.9%) P=.01 OR=3.2 (95% CI, 1.2–8.4)
Not reported Not reported Decrease Pre: 8/42 (19%) Post: 2/75 (2.7%) P < .001
Increase
CDC 2008
Decreased for superficial SSI only:
Clean, clean-contaminated Pre: 69/1,130 (6.1%) Post: 83/2,046 (4.1%) P=.01
Contaminated and dirty: Pre: 10/76 (13.2%) Post: 17/91 (2.2%) P=.006 Total SSI (P values not provided):
Clean, clean-contaminated Pre: 82/1,130 (7.3%) Post: 102/2,046 (5%) Contaminated and dirty: Pre: 18/76 (23.7%) Post: 17/91 (18.7%)
Anchalia 2011
India/Low-middle
Before/After Single hospital Population: not reported
Askarian 2011
Iran/Middle
Brisibe 2015
Nigeria
El Mhamdi 2014
Tunisia/Middle
Before/After Single hospital Adult (144)
Before/After Single unit Adults: number not reported
Before/After Single hospital Mixed population (508)
Multiple
En: Multidisciplinary committee
Ed: Training Ex: Protocols Ev: Surveillance, data feedback
Multiple
Ex: WHO safety checklist Ed: Training
OB/GYN
En: Commitment of the hospital management
Ex: Contract outsourcing, revolving fund scheme, policy
Multiple
Ex: WHO checklist Ev: Direct observation by senior physician
SAP, instrument sterilization
SAP, preoperative bathing, diabetes control, no/clip hair removal, iodine skin prep, closing operating room doors and limiting staff, instrument sterilization, sterile dressing change, surveillance
SAP policy Not reported CDC 1999
Decreased from 13% to 4.4% P values not provided.
Increase
Not reported No change Pre: 10.4% Post: 5.3% P=.10
Instrument sterilization
Not reported Not reported Overall: No change P=0.230 (Decreased in non-booked CS; P=.032)
Increase
Not reported Decrease Pre: 25/185 (13.5%) Post: 14/323 (4.3%) P < .001
(Continued)
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