Pycnogenol®
is linked to a
reduction of fine lines and wrinkles in research
SKIn bEnEfItS bacKED bY oVEr 40 YEarS of rESEarch collagen - pycnogenol binds with skin proteins collagen and elastin to help rebuild skin elasticity and structure. In one particular trial, daily supplementation with pycnogenol over a period of twelve weeks significantly increased collagen (type 1) production in subjects (via gene expression) by 41 per cent² contributing to reduction of fine lines and wrinkles. pycnogenol has also demonstrated the ability to inhibit enzymes such as matrix metallo-proteinases (mmps) -1, -2 and -9, which can otherwise break down collagen and elastin.³
hydration and elasticity - pycnogenol supplementation improves production of hyaluronic acid (the compound responsible for skin hydration), with one study showing a boost of up to 44 per cent after twelve weeks of supplementation! the subjects’ skin elasticity in average was elevated by 25 per cent after six weeks of pycnogenol and remained at this value until trial completion, with overall hydration raised by eight per cent. It was particularly noticeable in the skin of subjects who had dry skin before the study.²
circulation - pycnogenol boosts circulation to the skin by enhancing the body's natural production of nitric oxide, a powerful substance that allows blood vessels to relax and widen. this allows more oxygen and nutrient rich blood to reach the skin, as well as improving hydration delivery and waste removal4
.
antioxidant - pycnogenol has demonstrated powerful antioxidant capacity, combating free radicals which may degrade healthy skin cells in excess. pycnogenol contains proanthocyanidins, a family of powerful plant antioxidants. a six-week cohort trial demonstrated that pycnogenol supplementation significantly increased the blood plasma's antioxidant capacity in subjects, and these levels remain elevated for up to four weeks after supplementation!5
agIng at a SloWEr pacE the causes of accelerated aging are many, which is why versatile supplements such as pycnogenol with a range of different benefits have proven so successful in trials to help improve skin appearance. With an impressive list of evidence- based benefits, from antioxidant capacity to enhanced production of important dermal substances such as collagen and hyaluronic acid, pycnogenol supplementation is rising in popularity the world over for naturally healthy skin.
rEfErEncES: 1. Emerit I, chance b. free radicals and aging. free radical biology and medicine. 1993;14(6):705-706.
2. marini a, grether-beck S, Jaenicke t, Weber m, burki c, formann p et al. pycnogenol® Effects on Skin Elasticity and hydration coincide with Increased gene Expressions of collagen type I and hyaluronic acid Synthase in Women. Skin pharmacology and physiology. 2012;25(2):86-92.
3. Inhibition of nf-kappab activation and mmp-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (pycnogenol®). J Inflamm (lond) 27;3: 1, 2006
4. belcaro g, cesarone mr, Errichi bm, ledda a, Di renzo a, Stuard S, Dugall m, pellegrini l, gizzi g, rohdewald p, Ippolito E, ricci a, cacchio m, cipollone g, ruffini I, fano f, hosoi m.Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol®. clin appl thromb hemost 12: 318-323, 2006
5. Devaraj S, Vega-lópez S, Kaul n, Schönlau f, rohdewald p, Jialal I. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. lipids. 2002;37(10):931-934.
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