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<< Figure 1: Uniform phospholipid

encapsulated air bubbles (Courtesy Tide Microfluidics BV). >>

In figure 1 we provide uniform phospholipids encapsulated air bubbles generated by Tide Microfluidics that combines all of the advantages that will be found in the next generation of ultrasound based products. Here these micro spheres are smaller than red blood cells of less than 10 microns which vary by less than 5% in diameter regardless of the number of micro spheres individually generated by the machines. A generator that creates these structures has a rate of 1 million spheres per second. Not only is the generation rate of the micro bubbles much more than an order of magnitude greater than industry standard micro fluidic based practice, but it is also more than an order of magnitude more uniform. These are the characteristics that are the foundations for an industrial standard manufacturing practice.

The Tide Microfluidics generator is small and portable, allowing for diagnostic generation not only at the industrial manufacturer location but, more importantly, at point of care of an individual patient. It allows for continuous monitoring at a smaller controlled dosage, which can eliminate unwanted side effects. The Tide Microfluidics generator is one of the first of the next generation ultrasound medical products.

Tide Microfluidics

Dr. Wim van Hoeve is the founder of Tide Microfluidics with primary responsibility for the day- to-day work. He has worked for many years within the field both as a PhD student and more recently as an accomplished researcher

focusing purely on this technical innovation. He has the belief in this product which is underscored by the fact he has established this company, Tide Microfluidics, to bring the technology successfully to the medical market by applying his experience and knowledge, developed through collaborations within the network set-up around the technique.

Bernd Vinke, MSc, works for Tide Microfluidics as Business Development Manager after 11 years in international corporate banking. He has been involved in patent negotiations and fundraising since 1,5 years as an independent business advisor. He has worked for Tide Microfluidics since 1st of February 2014.

Dr. Steven Walsh is a Distinguished professor at UNM where also holds the Regents professor at UNM’s Anderson School of Management. He also is the institute professor for entrepreneurial renewal of industry at the University of Twente. He has many business service awards including the lifetime achievement award for Commercialization of Micro and Nano Technology Firms from MANCEF. He has also been named as a Tech All Star from the State of New Mexico Economic Development Department and has been recognised by Albuquerque the Magazine as a leader in service to the economic community. He is a serial entrepreneur that has helped attract millions of dollars in venture capital to these firms.

50 | commercial micro manufacturing international Vol 7 No.3

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