serum levels of theophylline, a common bronchodilator, by 20-30%, causing nervousness, tremor, or insomnia.


ALCOHOL Alcohol interacts with almost every medication and should therefore be avoided with concurrent use. It affects medications through its ability to change the liver’s capacity to filter medication through the body by either increasing or decreasing its effect. Alcohol can enhance the central nervous system’s depressant effects of benzodiazepines and antidepressants, producing excessive drowsiness and incoordination. As a gut irritant, alcohol, in combination with other irritants, including NSAIDs, may increase the risk of gastro-intestinal bleeding.


NUTRITIONAL SUPPLEMENTS Vitamins, minerals, essential fatty acids, and amino acids generally have fewer risks in conjunction with medication administration as they are normally found in the body, where they are required for physiological functions. Exceeding dosages of certain


nutritional supplements, however, raises concerns for concurrent use of certain medications.


5-HYDROXYTRYPTOPHAN 5-hydroxytryptophan (5HTP) is a naturally occurring amino acid and precursor to serotonin and melatonin. If it’s combined with selective serotonin re-uptake inhibitor (SSRIs)


medications (commonly prescribed anti-depressants), or even St John’s wort, can result in serotonin syndrome. This is a potentially life-threatening drug reaction from excess serotonin production and can cause symptoms that range from mild - shivering and diarrhoea – to severe, such as muscle rigidity, fever, and seizures.


VITAMIN E Vitamin E naturally exhibits blood- thinning effects. Daily administration exceeding 1000IU increases the risk of excess bleeding and should therefore be used with caution when combined with blood-thinning medication including warfarin.


VITAMIN K Supplementation and/or diets high in vitamin K such as green leafy vegetables (kale, spinach, broccoli and brussels sprouts) can counteract the effectiveness of blood thinning medication, increasing the risk of a stroke. It is recommended to check nutritional supplement lists to avoid the mistake of doubling up. As warfarin interacts with vitamin K in the body, it is important to keep vitamin K intake, supplemental or dietary, consistent each day.


IODINE Similarly, supplementation and/or diets high in iodine, including seaweed and seafood, can lower thyroid drugs’ efficacy. Caution is warranted when taken with thyroid medication.


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Development and Mastery of the Soul Century


HERBAL SUPPLEMENTS As herbs have similar actions to medications and can potentially cause toxicity and adverse reactions, it is recommended for individuals to be under the care of a healthcare practitioner with clinical experience in herbal medicine. Laxatives including senna, cascara,


and aloe increase gut motility, thereby accelerating the elimination of drugs. Sedatives such as kava, hops, and valerian potentiate further sedative effects. In some cases, however; herbs and


medications have shown to have a synergistic effect or prevent adverse reactions. Ginger, for example, can be used to avoid drug-induced nausea, while St Mary’s thistle can be taken to protect the liver from toxicity associated with drugs. Garlic also proves to prevent toxic metabolites produced from paracetamol.


ST JOHN’S WORT Commonly known for the treatment of anxiety, insomnia, and as a ‘natural anti- depressant’, St John’s wort stimulates the production of liver enzymes, resulting in lower concentrations of medication in the body, therefore should be avoided with any type of medication. Interactions with SSRIs, such as Prozac, can potentially lead to serotonin syndrome. Administering St John’s wort with warfarin can increase your susceptibility to blood clotting, strokes, and heart attack. Activation of liver enzymes by St John’s wort reduces cholesterol medication levels, elevating cholesterol in the blood. It also reduces


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