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SPECTROSCOPY 53


Second example of inconsistent feeding


manufacturer and supplier of inline process control technology to a range of manufacturing industries. Benefits gained from the


ColVisTec UV-VIS inline technology are:


l Continuous, nonstop determination of API concentration


l Detection of the distribution of API in molten polymer


l Residence time determination, with the answer available within 10 minutes


l Rapid validation of screw configuration


l Real-time monitoring of feed rate


Early adopters of this new technology have included leading pharmaceutical companies and academic institutions with a strong focus on pharmacology. ColVisTec works with extruder manufacturers, in particular Leistritz for the pharma sector, to give pharma industry customers an opportunity to try out UV-VIS based spectroscopy while the tests are run on Leistritz extruders.


Advantages to pharmaceutical sector ColVisTec claims that its innovative inline technology gives the end user the benefit


Graph shows feed set point


of significantly reduced time requirements for the development cycle, leading to a shorter time to market. Other benefits include high mixing efficiency, leading to less waste and greater output, and immediate detection of feeder problems or other incidents causing the API to deviate from the specified standard. ColVisTec is a technology


provider in the field of optical spectral photometry, UV-VIS spectrophotometry, colorimetric and optics. Te company generates improved efficiency and value through early detection and prevention of errors via process monitoring


and continuous quality control. Different probes provide solutions for a range of applications, including transparent and opaque materials. Particular areas of expertise


are applications for: polymers (extrusion application), powder (powder coatings and other powder form materials), mixing processes, paste material (cosmetics, paints, etc.), liquid coatings and paints, inks, pharmaceuticals (hot melt extrusion, wet granulation), food, beverages and other liquid materials.


For more information ✔ at www.scientistlive.com/eurolab


Thanks to ColVisTec, pharma industry customers can now try out UV-VIS based spectroscopy


Jan H. Johnsen is CEO of Colvistec. www.colvistec.de


www.scientistlive.com


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