PEER-REVIEW | DERMATOLOGY |


Figure 2 Female patient, aged 28 years. (A) Before treatment; (B) directly after treatment; (C) 1-hour post-treatment; (D) 2 hours post-treatment; (E) 2 hours post-treatment, with make-up; (F) 1-day post treatment; (G) 2 days post-treatment; (H) 3 days post-treatment. Treatment was carried out using Revive MN (AMIEA MED, MT.DERM GmbH, Berlin, Germany), Revive-HAP, 6-point needle plate


Further important effects of microneedling are fibroblast proliferation and collagen actuation, fibronectin and


extracellular matrix deposition, re-epithelialisation and angiogenesis.


2 weeks post-procedure, without any down-regulation


at 4 or 8 weeks. Compared with TGF-β1 and TGF-β2, TFG-β3 is regulated highly beyond the initial phase, which supports scarless healing and a normalised collagen structure5, 8


66 ❚ . October 2013 | prime-journal.com Further important effects of microneedling are


fibroblast proliferation and collagen actuation, fibronectin and extracellular matrix deposition, re-epithelialisation and angiogenesis. Collagen matures and remodels, and leads to a tightening of the skin. This


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