Compare RSA™
vials to your vials
The data table below illustrates the power and usefulness of RSA™ glass vials for chromatography. The data colored green in the chart shows how typical glass vials on the market today will adsorb basic compounds. When your analytes are in low abundance, ordinary glass vials can greatly skew your data. Vials made with RSA™ glass will provide more reliable data and not skew it.
Methodology Synopsis & Analysis: a test solution was placed in 3 sets of vials named (N1, N2 & N3) from each of the brands listed. The starting concentration of the test compounds was 5ug/ml. After standing in the vials for four hours, the final concentration of the analyte, as determined by HPLC, is reported for each group. The percent loss was calculated and is reported (% Loss) as well. The difference in the results between RSA™ glass vials and the others is one indication of the benefits of using RSA™ glass.
A second illustration of the benefits of RSA™ glass vials, is shown below and is colored red. This data shows leading vials on the market today may change the pH of your samples due to their surface chemistry where RSA™ glass does not.
Methodology Synopsis & Analysis: Methodology Synopsis & Analysis: DI water (pH 5.45) was placed in the same brands of vials as previously stated and several pH data points were taken at the start and randomly during a 4 hour test period. The data reported below in red is the ending pH readings from this test.
RSA™
This simple test and other more extensive tests have shown that glass vials do not cause any changes in the pH of the sample
solutions during the test period. Market leading vials can cause changes by more than 1.25 pH units.
TM
Adsorption & pH Change Comparison To Market Leaders N1
N2
Starting Points RSA Glass
MicroSolv Brand Basik Vials Brand F Brand N
N3 AVG
287.8 287.0 286.1 287 283.5 287.2 287.21 286
234.9 235.2 239.1 236 157.7 158.7 159.9 159 114.3 223.2
57.3 132
168.8 149.9 146.5 155 Green = Sample Adsorption Test
Red = pH Change Test
STARTING POINTS: Adsorption Test; 5ug/ml Chlorhexidene in water; pH Test; DI Water pH 5.45. RSA™ GLASS VIALS: Reduced Surface Activity Glass Vials. MICROSOLV™ BRAND VIALS: our leading line of autosampler vials and inserts on the market today. Made with pharmaceutical grade glass. BASIK™ BRAND VIALS: our popular brand of economy autosampler vials for when quality issues are mostly limited to fit and form. BRAND “F”: a leading brand of autosampler vials resold by many laboratory supply dealers. BRAND “N” is the leading brand of autosampler vials sold through dealers and private labeled by some of the largest instrument companies.
17.62 44.64 54.14 45.96
% LOSS pH 0.00 0.35
5.45 5.50
6.15 6.0
6.65 6.94
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