International Journal of Aesthetic and Anti-Ageing Medicine Informa Healthcare, 119 Farringdon Road, London, EC1R 3DA, UK
www.informahealthcare.com ISSN 2325-9817 (print) ISSN 2325-9825 (online)
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| GUEST EDITORIAL I
Dr Claude Dalle Dr Ashraf Badawi
N AESTHETIC MEDICINE, HAIR LOSS, DESPITE ITS HIGH INCIDENCE, IS OFTEN overlooked and managed in a cursory fashion. For physicians working in the aesthetic field, it is imperative to keep in mind that hair is an essential part of overall appearance and that loss of hair can significantly influence how a person is perceived by the outside world. When introduced, minoxidil and finasteride were important steps forward as they were the first hair-loss treatments with proven efficacy for androgenic alopecia and female pattern hair
loss. Two decades later, we know that there remains a need for a broader range of treatment options to successfully manage hair loss in both men and women. New and upcoming treatments for hair loss can be categorised into drugs, light-based devices, and
injectable biological agents. The most promising new drug is bimatoprost, a prostaglandin analogue initially developed to control the progression of glaucoma and management of ocular hypertension. As a side-effect, it was found to increase the growth of eye lashes by activating prostamide alpha F2 receptors in the hair follicle. Ongoing studies are currently in progress to document whether the drug is also efficient for the treatment of hair loss. With the now proven role of inflammation in hair loss in both genders, low level light therapy (LLLT)
devices, with their known anti-inflammatory effect, are gaining increasing acceptance as a treatment for hair. LLLT has been shown to increase hair count as well as hair shaft diameter. It is further believed to stimulate the metabolism in catagen and telogen follicles, resulting in an earlier transformation to active anagen phase. Two other emerging therapies are based on cell modulation principle. First is platelet-rich plasma
(PRP), a concentrated source of autologous platelets that contains several different growth factors and cytokines. Activated PRP has the potential to promote the proliferation of human dermal papilla cells and protect them from apoptosis. Clinical trials report an increase in hair thickness and computerised hair counts after injection of PRP into the scalp. The second is a hair stimulating complex (HSC) produced by neonatal cells grown under simulated embryonic conditions of hypoxia and suspension. Under these conditions, cells become multipotent and a significant upregulation of growth factors ensues. Two randomised, placebo-controlled clinical trials show that injections of HSC significantly increase total hair count and hair thickness. All of these upcoming approaches have the potential to become valuable treatment modalities for
hair loss. They allow physicians to choose optimal treatments based on the individual needs of each patient. Synergistic effects are likely when two or more treatments are used together as combination modalities are based on different mechanisms of action.
Neil Sadick, MD, FAAD. Clinical Professor of Dermatology at Weill Medical College of Cornell University
PRIME JOURNAL EDITORIAL BOARD BOARD MEMBER SPECIALISM Dr Wilmar Accursio
Anti-ageing & aesth. medicine France Endocrinologist Dermatology
Dr Janethy Balakrishnan Aesthetic & anti-ageing medicine Malaysia Dr Lakhdar Belhaouari Dr Anthony Benedetto Dr Philippe Berros Dr Dario Bertossi Dr Pierre Bouhanna Dr Fahd Benslimane Prof Wayne Carey
Plastic surgery
Cosmetic Dermatology Oculoplastic surgery Maxillofacial surgery
Dermatology – Hair surgery Plastic Surgeon Dermatology
Dr Claude Chauchard
Dr Christophe de Jaeger Geriatrics Dr Jacques Dequesne Prof Ilaria Ghersetich Dr Kate Goldie
Dr Monika Golkova Prof Eckart Haneke Dr Steven Hopping
Dr Marina Landau
Anti-ageing medicine Gynaecologist
Dermatology
Aesthetic Physician Neurologist Dermatology Plastic surgery
Prof Andreas Katsambas Dermatology Dr Mario Krause Dr David Lai
Anti-ageing medicine Anti-ageing medicine Dermatology
Egypt France
USA
Monaco Italy
France
Morocco Canada France France France Italy UK
Czech Republic Germany USA
Greece Germany
Hong Kong Israel
NORTH AMERICAN ADVISORY PANEL BOARD MEMBER SPECIALISM
Anoop Chaturvedi Lisa M. Donofrio Michael H. Gold Dr Z. Paul Lorenc
Anti-ageing Practitioner Cosmetic Dermatologist Dermatologist
Aesthetic Plastic Surgeon
STATE Texas
New York Tennessee New York
COUNTRY Brazil
BOARD MEMBER SPECIALISM Dr Gustavo Leibaschoff
Dr Sohail Mansoor Prof Leonardo Marini Dr Sly Nedic
Cosmetic surgery Dermatology Dermatology
Prof Dr Martino Neumann Dermatology & Venereology Prof Daniel Pella
Cardiology
Dr Chariya Petchngaovilai Dermatology Prof Ascanio Polimeni Dr Herve Raspaldo
Dr Christopher Rowland-Payne Dermatology Dr Neil Sadick
Dr Hema Sundaram Dr Pakpilai Thavisin Dr Patrick Treacy Dr Mario Trelles Dr Ines Verner Dr Octavio Viera
Dr Jean-Luc Vigneron Prof Bernard Weber Dr Sabine Zenker
Catherine Decuyper Wendy Lewis
Christophe Luino
Dermatology Dermatology
Neuro-endocrinology Facial plastic surgery
COUNTRY USA
UK Italy
Aesthetic & anti-ageing medicine South Africa Netherlands Slovakia Thailand Italy
France UK
USA USA
Dermatology & Anti-ageing medicine Thailand Aesthetic surgery Plastic surgery Dermatology
Ireland Spain Israel
Anti-ageing medicine; pediatry Spain Aesthetic dermatology Genetician
Dermatologist USA France
Luxembourg Germany
Industry expert & consultant France Industry expert
Industry expert & consultant France
BOARD MEMBER SPECIALISM Dr Ronald Mancini
Dr Nazanin Saedi
Dr S. Randolph Waldman Plastic Surgeon Dr Heidi A. Waldorf
Dermatologist STATE
Oculoplastic and Orbital Surgeon Texas Dermatologist
Pennsylvania Kentucky New York
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