| SKIN ANALYSIS | PEER-REVIEW I ARAMETERS
N COSMETIC MEDICINE: A NEW POINT OF CARE
P SKIN
Beniamino Palmieri, Stefania Capone, Valentina Rottigni and Torello Lotti discuss the use of a new skin analysis
system to test a number a dermal parameters before and after treatment with a dermal filler
ABSTRACT Skin biological parameters are usually measured with scales or digital photographs, but in recent years new devices based on physical and chemical principles have been developed to better define the effectiveness of drugs and instrumental therapies. The authors recruited 20 patients to perform a dermatologic evaluation with a new skin measuring device (Skin Tester). Skin Tester is a reliable and useful tool for clinical investigations in different medical and surgical branches, and provides the opportunity to stardardise skin pathology in different clinical environments.
BENIAMINO PALMIERI is Associate Professor at University of Modena and Reggio Emilia, Department of Surgical Science, Modena, Italy; STEFANIA CAPONE is a Master of Science at University of Modena and Reggio Emilia, Department of Surgical Science, Modena, Italy; VALENTINA ROTTIGNI is a Master of Science at University of Modena and Reggio Emilia, Department of Surgical Science, Modena, Italy; and TORELLO LOTTI is Full Professor & Chairman of Dermatology at University of Rome, Department of Dermatology and Venereology, Rome, Italy email:
valentina.rottigni@
alice.it
KEYWORDS skin, ultrasounds, diagnostic device, cosmetic
C
alterations during the ageing process (proteins, glycosaminoglycans, water, lipids).
Skin components and photoageing Collagen The age-related changes of the skin have been analysed on the basis of biochemical modifications. Proteins are investigated using spectroscopy, which
HARACTERISTICS OF THE SKIN AND changes as a result of ageing are usually measured using scales or digital photographs, with data comparison before and after a specific treatment. In recent years, however, some instruments
based on different physical and chemical principles have been developed, in order to have a more reliable evaluation to define the effectiveness of drugs and therapies. To identify
specific
pathological skin parameters, it is important to be cognisant of the changes which the skin undergoes during ageing. Waller and Maibach1,2
described the
features of the different layers of the skin and their biochemical
analyses molecular compound conformation and aspartic acid racemisation to detect skin proteins, such as collagen and elastin accumulation. Collagen, which includes approximately 70–80% of the
dry weight of the dermis, is responsible for the skin’s tensile strength. Each collagen molecule consists of three polypeptide chains, containing approximately 1000 amino acids in their primary sequence. In collagen molecules, the α-chains are wrapped around each other to achieve a triple helical formation2
. The ratio of types I and III collagen fibres in To identify
specific pathological skin parameters, it is important to be cognisant of the
changes which the skin undergoes
during ageing.
the skin remain constant throughout childhood and young adult life. However, as we age, the proportion of type III collagen in the dermis increases and the bundle width changes significantly, reflecting an impaired synthesis of type I collagen in older skin3 Oikarinen4
. showed that collagen synthesis
gradually declines in chronologically aged skin, and in protected skin the epidermis becomes thinner, especially after the seventh decade of life. On the contrary, an excessive exposure to
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