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references 2. 3.


4. 5.


6. 7. 8. 9.


10. 11.


12. 13. 14.


15. 16.


17. 18.


1. Websites: Crohn’s and Colitis Foundation of Canada (www.ccfc.ca), Crohn’s and Colitis Foundation of America (www.ccfa.org), National Institutes of Health information (www.health.nih.gov)


19. Shaw SY, Blanchard JF, Bernstein CN. Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease. Am J Gastroent 2010: 105: 2687-92.


Koloski NA, Bret L, Radford-Smith G. Hygiene hypothesis in inflammatory bowel disease: a critical review of the literature. World J Gastroenterol 2008; 14: 165-73.


THE IMPACT OF INFLAMMATORY BOWEL DISEASE IN CANADA 88


Hugot JP, Zouali H, Lesage S. Lessons to be learned from the NOD2 gene in Crohn’s disease. Eur J Gastroenterol Hepatol 2003; 15: 593-7.


Heresbach D, Gicquel-Douabin V, Birebent B et al. NOD2-CARD15 gene polymorphisms in Crohn’s disease: a genotype-phenotype analysis. Eur J Gastroenterol Hepatol 2004; 16: 55-62.


Russell RK, Drummond HE, Nimmo EE et al. Genotype-phenotype analysis in childhood-onset Crohn’s disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease. Inflamm Bowel Dis 2005; 11: 955-64.


Brant SR, Wang MH, Rawsthorne P et al. A population-based case-control study of CARD15 and other risk factors in Crohn’s disease and ulcerative colitis. Am J Gastroent 2007; 102: 313-23.


Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature 2001; 411: 603-6.


Hugot JP, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease. Nature 2001; 411: 599-603.


Halfvarson J, Bodin L, Tysk C et al. Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics. Gastroenterology 2003;124: 1767-73.


Orholm M, Binder V, Sorensen TI et al. Concordance of inflammatory bowel disease among Danish twins – results of a nationwide study. Scand J Gastroenterol 2000; 35: 10075-1081.


Monsen U, Bernell O, Johansson C et al. Prevalence of inflammatory bowel disease among relatives of patients with Crohn’s disease. Scand J Gastroenterol 1991; 26: 302-6.


Binder V, Orholm M. Familial occurrence and inheritance studies in inflammatory bowel disease. Neth J Med 1996; 48: 53-6.


Pinsk V, Lemberg DA, Grewal K et al. Inflammatory bowel disease in the South Asian pediatric population of British Columbia. Am J Gastroent 2007: 102: 1077-83.


Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 2004: 126: 1504-17.


Molodecky NA, Soon IS, Rabi D et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142: 46-54.


Carter MJ, Lobo AJ, Travis SPL. Guidelines for the management of inflammatory bowel disease in adults. Gut 2004; 53 (Suppl 5): v1-16.


Panaccione R, Fedorak RN, Aumais G et al. Canadian Association of Gastroenterology Clinical Practice Guidelines : the use of infliximab in Crohn’s disease. Can J Gastroenterol 2004; 18: 503-8.


Silverberg MS, Satsangi J, Ahmad T et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005; 19 Suppl A: 5-36


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