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ARTICLE | DERMONUTRITION |


NUTRITION: WHAT DO WE KNOW?


ACNE AND


Lara Tripo and Ilaria Ghersetich review the available evidence for a link between diet and nutrition, and the development of acne


ABSTRACT


LARA TRIPO, MD, is Dermatology Resident, Division of Clinical, Preventive and Oncologic Dermatology, Department of Critical Care Medicine and Surgery, University of Florence; and ILARIA GHERSETICH, MD, (pictured) is Dermatology Consultant, Division of Clinical, Preventive and Oncologic Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Casa di Cura S.Chiara, Piazza Indipendenza 11, 50129 Firenze, Italy


email: lara_tripo@yahoo.it


Acne is one of the most common skin conditions. In Western countries it affects almost all people aged 11–17 years to some degree. Late-onset acne occurs most commonly in women over 25 years of age. It is now well established that acne is a disease of the pilosebaceous unit, in particular of the sebaceous glands associated with the skin’s hair follicles. It is well-known that acne is influenced by a genetic predisposition, but that the onset of the disease is mediated by environmental factors, such as endogenous and exogenous hormones, diet and cigarette smoke. The relationship between diet and acne onset has been a controversial


persists ® as well as many other chronic conditions ® into adulthood. It appears earlier in girls, but affects more boys and often in a more severe way during the mid-teen years. Late-onset acne most commonly occurs in women aged over 25 years and is related to circulating androgens. It is now well established that acne is a disease of the pilosebaceous


A


KEYWORDS acne, dairy products, high-glycaemic foods


38 ❚


unit, in particular of the sebaceous glands associated with skin-hair follicles1


. These glands produce a holocrine secretion, formed by the


complete disintegration of the granular cells, the major function of which is to excrete sebum. The clinical features of acne include increased grease production (seborrhoea), non-inflammatory lesions (better known as open and closed comedones), and inflammatory lesions (papules, pustules, nodules and cysts) with varying degrees of scarring.


July/August 2012 | prime-journal.com


topic for a number of years. All reviews prior to 2007 have found no significant correlation between acne and diet. Recently, however, the association of some nutrients with acne onset has been called back into question, especially the evidence that consumption of dairy products and high-glycaemic foods can exacerbate acne. Despite the fact that more prospective studies are needed to solve such uncertainties, dermatologists cannot completely dismiss the association between acne and diet any longer. Counselling their patients to reduce high glycaemic-load and dairy intake could then be of help in managing this dermatological disease.


CNE IS ONE OF THE MOST COMMON SKIN conditions. In Western countries it affects, to some degree, almost all people aged 11–17 years (almost 85% of this population), and is moderate to severe in approximately 15–20% of people1


. Despite being generally considered a teenage disease, it often It is now well


established that acne is a disease of the pilosebaceous unit, in particular of the sebaceous glands associated with skin hair follicles.


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