INGREDIENTS EXTREMES
EXTREME INGREDIENTS FROM SPACE TO GOLD MINES
Kyle S Landry and Julia Gropman from Delavie Sciences ask what do we get when we push organisms to their limits?
O
rganisms that thrive in extreme conditions are known as extremophiles. Extremophiles have
adapted to survive various strenuous conditions including, but not limited to, extreme temperatures, pH levels, atmospheric conditions and everything else in between. Some extremophiles can even live off toxic compounds. Recently, a few extremophiles, such as tardigrades and radiodurans, have been highlighted in various news outlets.
They have even embraced pop culture, with the most recent new species of tardigrades being named after a Harry Potter character.
The promise of extremophiles goes well beyond pop culture and science trivia.
Extremophiles are currently being studied for new pharmaceutical, commercial and industrial applications. However, the use of extremophiles in the consumer care space is in its infancy.
EXTREMOPHILE RESEARCH How does one start the journey into the world of extremophiles?
20 January 2023
You need to know what you are looking for and where to look. Most extremophiles have unique adaptations that help them survive in their niche environment.
For example, organisms that grow in elevated temperatures need to protect themselves from rapid oxidation and DNA mutations. To do this, they have evolved efficient mechanisms that could, in theory, be beneficial to skin care. Novel molecules, enzymes, protective peptides and extracellular products, such as gums, surfactants and pigments, all have a place as functional or active ingredients.
Extremophile research is primarily focused on industrial processes, environmental remediation and biotechnology applications.
One of the most famous extremophile breakthroughs was the discovery of the Taq polymerase, the DNA polymerase that is the foundation for the polymerase chain reaction (PCR). The PCR revolutionised the
biotechnology landscape and paved the way for genomic sequencing, DNA-based criminal forensics, genetic modification and almost every other ‘-omic’ based technique.
Other uses of extremophile-based technology can be found in cleaning products (laundry detergent, degreasers, etc) and food manufacturing processes (sugar, starch and protein manufacturing).
SKIN CARE FROM SPACE From 1,500m below the surface of the Earth to 402km above, Delavie Sciences taps into the extremophile world to create innovative ingredients for the skin care market.
Delavie Sciences is part of EdenRoc Sciences, a privately held biotechnology company which cultivates world-class life sciences companies. With help from researchers like Dr David Sinclair, a Professor at Harvard Medical School, Delavie’s research targets some of the most impactful segments within the industry. For example, Delavie Sciences’ patented ingredient, Bacillus Lysate, is an ‘out-of-this-world’ SPF booster and antioxidant.
The ingredient is derived from a specific strain of Bacillus spp, originally identified as a contaminate in a spacecraft assembly facility, that survived exposure to space conditions
cosmeticsbusiness.com
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