performance. Supplementation of 1500 – 2500 FTU/kg phytase (superdosing) aims to achieve near complete breakdown of phytate (IP6
) and the lower isomers (IP5 – IP2 ). Even in small amounts, phytate and its lower isomers can reduce
the bioavailability of protein and divalent metal ions. This has particular relevance to iron, with trial results at 21 days post-weaning showing that reduced phytate content in piglet ileal digesta was associated with an increase in haemoglobin levels. Furthermore a weaner pig study demonstrated that increasing doses of modified E. coli phytase linearly increased iron status measured as the proportion of haematocrit, indicating increased proportion of red blood cells in the blood (Figure 2).
Figure 2. Effect of dietary iron and Quantum Blue phytase dose on iron status of piglets at 21 day post-weaning (measure as proportion of haematocrit) (Iron P<0.05, Phytase P<0.05, Iron × phytase interaction P<0.05. Laird et al., 2017)
20 22 24 26 28 30 32 34
Effect of Quantum Blue and Iron Levels on Hematocrit (%) concentration 32.2 29.2 26.8 25.2 27.2 30.2
Low Fe (100 ppm) 0 500 2500 Quantum Blue (FTU/kg) This improved iron status through increasing dietary iron
supplementation or high doses of phytase, as measured by haemagloblin and haematocrit, was also reflected in an improved ADG and FCR from weaning to 21d (Figure 3). The highest performance at 21 days post-weaning was observed in pigs fed diets containing high iron (320 ppm) and high phytase (2500 FTU/kg).
Figure 3. Effect of dietary iron and Quantum Blue phytase dose on FCR from weaning to 21 day post-weaning (Iron P<0.11, Phytase P<0.01, Iron × phytase interaction P<0.25. Laird et al., 2017).
FCR (g/g) 1.45
1.35 1.4
1.25 1.3
1.15 1.2
1.05 1.1
Low Fe (100 ppm) 0 FTU/kg phytase 500 FTU/kg phytase
High Fe (320 ppm) 2500 FTU/kg phytase
Low Fe = 100 ppm and High Fe = 320 ppm With a continued focus on improving post-weaning performance
understanding the iron status of newly weaned pigs is worth further investigation. One application that may be beneficial in improving iron status of the post-weaned piglet is the use of high doses of a modified E Coli phytase to unlock the dietary iron potential bound by phytate.
FEED COMPOUNDER MARCH/APRIL 2018 PAGE 29 Fe: P < 0.11, Phytase, P < 0.01 Fe x Phytase, P < 0.25
High Fe (320 ppm)
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