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Supplements & functional ingredients


While the research may remain inconclusive on omega-3, most scientists can agree on the many benefits of eating a fish-rich diet.


In the US, to give one example, an estimated 8% of adults actively take omega-3 in some form. Yet if the packaging says it can fight a bewildering range of ailments, there’s one area where the seduction of omega-3 remains unmatched: heart health. This appears to be the result of a certain American company, whose product is proudly called ‘Heart Health’ and tells readers in capital letters that it’s designed for ‘cardiovascular maintenance’.


“It is important for individuals with cardio vascular disease (CVD) to have adequate omega-3 intake, either from foods or supplements, to improve cardiovascular health.” Professor Simin Liu


Of course, the particular allure of cardiovascular health isn’t difficult to understand. According to the WHO, 16% of all deaths worldwide are due to heart disease, meaning anything that offers to keep users safe is bound to be popular. Explore the specifics, however, and the situation soon becomes less straightforward – something even the manufacturers of ‘Heart Health’ are obliged to admit. Turn the box over and you’ll see a disclaimer noting its claim of ‘cardiovascular maintenance’ hasn’t actually been evaluated by the FDA.


That concession, in turn, hints at a broader truth: despite being recommended for some 50 years, what omega-3s can do for heart health remains uncertain. And beyond the fundamentals, other problems persist too. What form, for instance, is the best way to take omega-3? How does it interact with other nutrients to keep the body safe? None of these questions necessarily have simple answers – even as new research promises to offer exciting new insights.


14


The heart of the matter


Arguments around the precise link between omega-3 and heart health have been raging for decades. Since the first flush of optimism in the 1970s, when a team of Danish scientists uncovered the probable benefits of the fats among the natives of Greenland, Philip Calder says that “the pendulum has swung one way and another many times” over recent years.


Listen to the University of Southampton professor


and it’s hard to disagree. Through the 1980s and 1990s, for example, Calder describes how a range of studies investigated whether measures like lipids and blood pressure could positively be linked to omega-3. Many researchers concluded that fatty acids could indeed keep blood pressure low, and along the way cut the risk of heart disease. From there, scientists moved on to look at people who had already suffered a heart attack, with one Italian study known as ‘GISSI-Prevenzione’ suggesting omega-3 could reduce the danger of having a second cardiovascular episode. More recent attempts to replicate that famous 2001 project have failed, with one suggestion being new drugs like statins have made it hard to repeat experiences precisely. To put it another way, the scientific evidence remains distinctly muddled – even if Calder is eager to emphasise that the broad links between omega-3s to heart health “is still robust”. Nor is he alone in coming to a basically positive conclusion on decades of work. “It is important for individuals with cardiovascular disease (CVD) to have adequate omega-3 intake, either from foods or supplements, to improve cardiovascular health,” emphasises Simin Liu, a professor of epidemiology and medicine at Brown University. “New observational studies generally support the notion that a higher intake of fish reduces cardiovascular disease risks.”


Ingredients Insight / www.ingredients-insight.com


Jakub Rutkiewicz/Shutterstock.com


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