Luminescence, UV & Microplate Readers Medical dyes to benefit fluorescence-guided surgery


Provepharm is advancing surgical precision with plans to launch two innovative dyes in 2026, supporting minimally invasive and fluorescence-guided robotic surgery. The move marks a strategic shift toward R&D- driven growth and cutting-edge visualisation solutions.


The company has partnered with Sagent Pharmaceuticals to distribute Bludigo®


- an


FDA-approved injectable indigo carmine - alongside its upcoming diagnostic dyes in the US, using Sagent’s market expertise and commercial reach. Internationally, Provepharm will roll out its new dyes through its global distributor network.


Reagents


Sharper, brighter dyes for spatial imaging


“Our goal is to create the most advanced range of surgical dyes by 2030,” said Hélène


Thomas, Deputy CEO of Provepharm. “We are combining our deep R&D expertise with next-generation fluorescence technology to deliver highly selective, reliable, and stable dyes for surgeons worldwide.”


Provepharm’s ‘Smart Dyes’ platform will focus on enhanced purity, stability, and


Clinical, Medical & Diagnostics


visualisation performance, helping surgeons see more clearly during complex procedures, particularly in oncology. The company’s approach emphasises efficiency, precision, and patient safety, building on 25 years of expertise in high-quality medical dyes.


The medical dye market is expanding rapidly, with demand fuelled by increasingly complex surgeries and widespread adoption of imaging and fluorescence-guided techniques. Provepharm is positioning itself at the forefront of this growth, combining scientific innovation with global partnerships to reshape surgical visualisation.


More information online: ilmt.co/PL/QKmQ 66537pr@reply-direct.com


High-throughput UV and fluorescence quantification


Biotium has expanded its Tyramide Signal Amplification (TSA) portfolio with TyraMax™ Amplification Dyes and Kits, designed for superior brightness, photostability, and buffer stability. The dyes deliver up to 100-fold higher detection sensitivity compared to conventional immunofluorescence, making them ideal for multiplex fluorescence and advanced spatial biology workflows, including tissue mapping and cyclic immunofluorescence (CycIF).


The TyraMax™ line offers the widest range of colours, from blue to near-infrared, allowing researchers to design complex multiplex panels with maximum flexibility. All dyes, including near-IR options, remain stable in amplification buffer for at least 24 hours, supporting automated staining workflows and reducing the risk of signal loss due to oxidation.


“Many spatial biology methods still rely on dyes that underperform in brightness or stability,” said Lori Roberts, PhD, Director of Bioscience at Biotium. “TyraMax™ dyes address these limitations, enabling scientists to build larger, more reliable multiplex panels for cutting-edge imaging applications.”


TyraMax™ dyes are available as standalone reagents, trial sizes, or ready- to-use multiplex sets such as 3-Plex and 5-Plex Amplification Dye Sets with DAPI. Compared to leading competitors, TyraMax™ provides brighter, more stable signals at a more accessible price point, giving researchers confidence to optimise complex panels and workflows.


With TyraMax™, Biotium empowers scientists to achieve higher sensitivity, sharper signals, and more consistent results in spatial biology, tissue mapping, and multiplex fluorescence imaging. The dyes and kits are available through Biotium and authorised distributors worldwide.


More information online: ilmt.co/PL/vlRd 66607pr@reply-direct.com


Beckman Coulter Life Sciences has introduced fully automated UV and fluorescence-based nucleic acid quantification on its Biomek i-Series workstations. Integrating the eviDense UV Photometer and eviFluor Duo fluorometer directly onto the deck, laboratories can measure nucleic acid concentration and purity (260/280 and 260/230 nm) and perform fluorometric assays without manual intervention.


The system combines liquid handling automation with real-time absorbance and fluorescence detection, enabling researchers to quantify nucleic acids from purified or complex samples with minimal sample loss. Non-destructive analysis allows immediate downstream


processing or recovery, while fluorometric measurements of 96 samples can be completed in just 20 minutes.


This integration streamlines workflows for NGS library preparation, extraction,


Analysers


and other molecular biology applications, reducing hands-on time and eliminating variability associated with manual pipetting and measurement. Both UV and fluorescence detection operate seamlessly within the automated platform, supporting reproducible, high-quality data for genomics, drug discovery, and research laboratories.


By merging high-precision optics with automated liquid handling, Beckman Coulter is helping labs increase throughput, reliability, and workflow efficiency - all while ensuring sample integrity and measurement consistency.


More information online: ilmt.co/PL/0KZV 66615pr@reply-direct.com


Cleaner signals for multi-colour flow cytometry


Thermo Fisher Scientific’s Invitrogen™ UltraComp eBeads™ Spectral Unmixing Beads, designed to make spectral and conventional flow cytometry more precise and reliable. These next-generation beads mimic real cells, helping researchers separate overlapping fluorescent signals, reduce background noise, and confidently quantify complex or rare cell populations.


High-parameter flow cytometry provides a detailed view of cellular phenotypes, but traditional compensation solutions can introduce errors or false signals. UltraComp eBeads address these challenges by offering bright, consistent fluorochrome signals with minimal autofluorescence. They support antibodies from mouse, rat, hamster, rabbit, and recombinant human sources and


Flow cytometry


Each drop contains both positive and negative populations, producing clear, distinct peaks for quick and easy panel setup - even for high-parameter experiments. Researchers in immunology, immuno- oncology, and flow cytometry core facilities can now streamline workflows while maintaining clean, reproducible data.


“UltraComp eBeads deliver the accuracy and reliability researchers need to tackle complex cellular analyses,” said Trisha Dowling, VP/ GM, Flow and Imaging Technologies. “They provide clearer signals, fewer errors, and confidence in every experiment.”


are compatible with all major laser lines, including UV, violet, blue, green, yellow-green, red, and IR.


More information online: ilmt.co/PL/wGY4 66613pr@reply-direct.com


New Anti-GFP antibodies enhance fluorescent protein detection Rabbit Anti-GFP, expanding its


Jackson ImmunoResearch introduces AffiniPure®


portfolio of secondary antibodies for life science research.


GFP is widely used to monitor protein expression and localisation within cells. Anti- GFP antibodies enhance detection, enabling researchers to work in conditions where direct GFP fluorescence may be limited.


Affinity-purified and polyclonal, the new Rabbit Anti-GFP antibody detects Aequorea victoria


GFP and its variants, including EGFP, ECFP, and EYFP. Available conjugated to Alexa Fluor® dyes and other reporters, it provides strong signal amplification for diverse applications.


Now available in the USA and Europe through Jackson ImmunoResearch and global distribution partners.


More information online: ilmt.co/PL/bjl9 63925pr@reply-direct.com


Clinical, Medical & Diagnostics


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