SPOTLIGHT FEATURE Spectroscopy


FTIR


Every stage, every spectrum: Confident FTIR verification for labs


Anton Paar’s Lyza series FTIR spectrometers provide a rapid, reliable, and non-destructive solution for quality control across the entire workflow. The permanently aligned interferometer ensures stable spectral performance and is backed by a 15-year warranty on key optical components, giving laboratories long-term reliability and confidence.


“For pharmaceutical and medical cannabis testing laboratories, confirming the identity and quality of materials, intermediates, and final formulations at every stage is essential to ensuring batch integrity,” said Uršula Vide, PhD, Product Manager for the Lyza series.


“High sample volumes and complex workflows demand analytical tools that deliver fast, consistent, and traceable results while supporting compliant manufacturing across multiple users and shifts. With Lyza, we designed a system that meets these challenges head-on – offering stability, simplicity, and the standardised approach laboratories need as their testing requirements evolve.”


In pharmaceutical applications, the Lyza series simplifies method setup and standardises measurements through guided workflows and methods at the push of a button. Its modular, plug-and-play cell design allows seamless switching between ATR, transmission, and other techniques to accommodate diverse sample types. Lyza also supports both commercially available and customisable spectral libraries, enabling laboratories to tailor QC protocols to their specific materials, intermediates, and final products.


For medical cannabis and cannabinoid-based


formulations, Lyza offers a fast and robust alternative to traditional chromatographic methods for CBD quantification. ATR technology enables direct measurement of cannabis oils with minimal sample preparation – no dilution, reagents, or complex steps. Characteristic absorbance peaks correlate directly with cannabidiol content, enabling precise and reproducible quantification across a wide concentration range. Additionally, Anton Paar’s proprietary CBD oil library ensures reliable verification of finished products.


Integrated with Spectroscopy Suite Premium, Lyza delivers fully compliant and traceable operation. Features such as audit trails, user management, electronic signatures, method versioning, and structured result reporting support regulatory compliance, including 21 CFR Part 11. Combined with stable FTIR performance and guided workflows, the Lyza series provides laboratories a future-ready solution for confident material verification.


More information online: ilmt.co/PL/JoRL 66523pr@reply-direct.com


Dried pet food analysis using NIR spectroscopy Infrared (IR)


Traditional techniques to assess moisture, protein, fat, and ash in pet food are often both time-consuming and labour-intensive. In contrast, NIRS offers a rapid, non- destructive alternative, delivering results in around one minute, all with minimal preparation.


In a study, 199 dried dog and cat food samples from various suppliers were analysed using the OMNIS NIR Analyser Solid. The system measured a mix of both whole and ground samples in diffuse reflection mode, with rotating sample cups to ensure representative spectra. Calibration models were then developed by correlating NIR spectral data with reference values obtained through established ISO methods.


The results not only demonstrated a strong prediction performance for critical quality parameters, but they also highlight the significant time savings NIRS provides in comparison to standard ISO methods,


New Raman spectrometer streamlines non-destructive QC testing


Thermo Fisher Scientific has introduced the DXR3 SmartRaman™+ Raman Spectrometer, designed to streamline quality control across pharmaceutical and industrial environments. The system combines non-destructive Raman spectroscopy with automated sampling and custom sample holders, allowing testing directly through final product packaging. This preserves sample integrity while detecting defects or contaminants with confidence.


Quality control can be time-consuming and labour-intensive. The DXR3 SmartRaman™+ accelerates workflows, reduces manual handling, and simplifies operator training through intuitive hardware and software. This helps teams make confident decisions, minimise sample waste, and maintain consistent product quality from production through to packaging.


“The DXR3 SmartRaman™+ brings efficiency and confidence to QC workflows,” said Ganesh Prasad, General Manager for Vibrational Spectroscopy Products at Thermo Fisher Scientific. “By combining non-destructive Raman analysis, automated sampling, and intuitive operation, it helps teams detect contaminants faster and maintain consistent quality across manufacturing processes.”


The spectrometer supports both 532 nm and 785 nm lasers, giving flexibility to analyse liquids, powders, and finished packaged products. It can be used for a range of applications, including fill-and-finish quality


Circular Dichroism beyond


Circular Dichroism (CD) spectroscopy is central to structural biology and chiral analysis. However, in 2025, many laboratories still rely on camphor-10-sulfonic acid (CSA) or ammonium camphorsulfonate (ACS) for instrument verification. These traditional methods require fresh preparation, are prone to hygroscopic error, and only validate a single peak near 290 nm. The result: The visible range goes untested, and compliance is left exposed.


reducing multi-hour laboratory procedures to a single rapid scan.


With a pre-calibrated NIRS model available for pet food, Metrohm’s OMNIS NIR is an effective solution for routine quality control, helping manufacturers meet regulatory standards whilst also optimising production efficiency.


Read the case study.


More information online: ilmt.co/PL/xD4X 66499pr@reply-direct.com


Starna leads the industry with its Certified Reference Materials (CRMs) for CD. Each set contains permanently flame-sealed quartz cells – Blank, R,R, and S,S enantiomers – spanning both UV and visible regions (190–700 nm and 400–700 nm). Ready-to-use, these references eliminate weighing and waiting, removing preparation variability and ensuring reproducibility across instruments and locations.


Certification extends beyond static tables. Every set features a continuous Δε(λ) model and U95 uncertainty envelopes, so users can verify performance at any wavelength with confidence. For those who prefer a rapid check, certificates highlight key maxima and minima: anchor points at 210, 237, 274, and 545 nm for UV, and 446, 479, 545, and 605 nm for VIS. Spot-checking instrument performance becomes straightforward, with no need for complex


Raman


control in pharmaceuticals, detecting adulterants in consumer goods, and verifying defects in industrial laboratories.


Designed for ease of use, the DXR3 SmartRaman™+ integrates smoothly into existing workflows. Its intuitive software and plug-and-play connectivity allow operators to get up to speed quickly while minimising manual input. The system also supports OPC UA connectivity, enabling seamless integration with manufacturing platforms for consistent data management and QC reporting.


By combining speed, accuracy, and non- destructive testing, the DXR3 SmartRaman™+ delivers faster, safer, and more reliable quality control. It helps teams safeguard product quality at every stage of production, from initial manufacturing to final packaging, making it a versatile tool for both pharmaceutical and industrial environments.


More information online: ilmt.co/PL/Mv5D 66512pr@reply-direct.com


Circular Dichroism (CD)


single-point checks: First accredited ISO 17025 CRMs deliver spectrum-wide confidence


calculations. Certificates are valid for two years, offering lasting assurance between renewals.


As the first and only producer with an accredited (UKAS) scope for CD CRMs, Starna combines ISO 17034 production and ISO/IEC 17025 calibration for unmatched traceability and compliance. This achievement ensures every set is certified with globally recognised traceability for audit-ready documentation and spectrum-wide reliability.


For regulated environments, the advantages are clear: objective acceptance criteria, reduced operational risk, and data integrity you can defend. Say goodbye to stresses that result from last-minute scrambling to prepare unstable CSA solutions, or worrying about gaps in instrument calibration. With Starna UKAS-accredited CD spectroscopy standards, you can demonstrate compliance and reproducibility across the full spectrum.


Ready to move beyond single-point checks? Request a certificate sample or technical briefing today to experience how Starna Certified Reference Materials can transform your laboratory’s approach to CD instrument qualification.


More information online: ilmt.co/PL/LwWd 65529pr@reply-direct.com


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LABMATE UK & IRELAND - FEBRUARY 2026


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