Automate LC Purification & High-Purity Compound
Recovery with UFPLC Shimadzu’s UFPLC is the industry’s first Ultra-Fast Purification LC instrument that fully automates recovery of highly purified target compounds from complex samples.
Conventional workflows utilising preparative liquid chromatography yield fractions with significant water content which can take several hours to evaporate and typically cannot be completely removed. The UFPLC offers a single automated workflow that utilises on-line fraction trapping as an alternative to traditional fraction collection, allowing elution of collected compounds in highly volatile organic solvents that can easily be evaporated, resulting in ultra-high purity compounds in significantly reduced time. The instrument is controlled by a dedicated walk-up software designed for users to easily set conditions for chromatographic separation and isolation of target compounds, trapping, purifying, eluting and collecting highly purified compounds. The Nexera UFPLC greatly improves the efficiency of preparative fraction collection and purification workflows in pharmaceutical, food, chemical and other industries as well as research organisations. The main functions of the UFPLC system include:
• Automation of fraction post-processing (desalting, solvent removal, counter ion switching) • Up to 90% faster sample evaporation • Targeting major peaks or small unknown impurity peaks • Generating highly reproducible pure samples More information online:
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Tackling Helium Shortage Compendium - Helium Saving Options & Alternative Gases for
GC/GCMS This comprehensive resource aims to address the growing concerns surrounding helium scarcity and offers valuable insights into helium saving/ reduction options as well as alternative carrier gas options.
Gas chromatography plays a vital role in a wide range of scientific applications, including pharmaceuticals, environmental analysis, food and beverage testing, and more. However, the reliance on helium as a carrier gas has become a pressing issue due to its limited availability and rising costs. In response to this challenge, Shimadzu has taken a proactive approach by developing strategies to conserve helium and explore alternative gas options.
The compilation of resources, accessible at
www.shimadzu.co.uk/gas-options, serves as a comprehensive guide for laboratories seeking to reduce helium consumption and ensure uninterrupted chromatographic analysis. It offers a wealth of information on helium-saving techniques, optimised instrument settings, and innovative technologies designed to maximise efficiency while minimising helium usage.
“At Shimadzu, we are committed to providing sustainable solutions that empower laboratories to overcome challenges and improve their analytical capabilities,” said Andrew Clissold, GC/GCMS Product Manager at Shimadzu UK. “With the growing helium scarcity, it is crucial for laboratories to adopt helium conservation strategies and explore alternative gas options. Our new webpage serves as a valuable resource, offering practical insights and recommendations to address this pressing issue.”
The webpage highlights various strategies for helium conservation, such as the use of carrier gas selector valve, automated software features and column dimension optimisation. These measures not only help laboratories save helium but also enhance analytical performance and reduce operational costs.
In addition to helium-saving techniques, the resource delves into the realm of alternative carrier gases, presenting laboratories with viable options in the absence or shortage of helium. Shimadzu provides comprehensive information on the benefits, limitations, and best practices for utilising other gas options, including hydrogen and nitrogen. By leveraging these alternatives, laboratories can achieve reliable and reproducible chromatographic results.
Experience New Benchmarks
The Nexera series of UHPLC systems offers ground- breaking technology in terms of intelligence, effi- ciency and design. Advanced AI capabilities and lab management using the Internet of Things (IoT) have been integrated to monitor performance and resource allocation. They make the new Nexera systems a leading-edge and user-friendly solution for versatile industries, setting new benchmarks in UHPLC.
Intelligent auto-diagnostics and auto-recovery features e.g. real-time mobile phase level monitoring, auto- recovery from air bubbles and management of con- sumable consumption
www.shimadzu.co.uk/new-benchmarks
Efficient process automation and fast, reliable performance from startup to shutdown providing automated workflow, maximized throughput and dramatically increased analysis capacity
Compact design offering ease-of-operation on a reduced footprint
Shimadzu’s expertise and commitment to innovation have enabled the development of cutting-edge technologies that facilitate the adoption of alternative carrier gases.
To further support laboratories in their transition towards helium conservation and alternative gas options, Shimadzu offers comprehensive training, technical support, and application guidance. Their team of experts is dedicated to assisting customers in implementing sustainable practices and achieving optimal chromatographic performance.
Shimadzu invites scientists, researchers, and laboratory professionals to visit the gas options webpage at
www.shimadzu.co.uk/gas-options and explore the wealth of resources available. In addition, any interested parties are encouraged to contact Shimadzu directly to discuss the options available in more detail. By embracing helium conservation strategies and employing alternative carrier gases, laboratories can drive scientific progress while minimising the environmental impact and operational costs associated with helium usage.
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