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ANALYTICAL INSTRUMENTATION


Rapid, direct mass spectrometry characterisation of difficult samples


What are the ins and outs of a SPE workflow?


Due to its versatility and efficiency, including the low environmental impact and reduced volume of solvents required, solid phase extraction (SPE) is the preferred method for sample cleanup and trace enrichment for many analytical laboratories. Large application fields, like contaminant isolation from environmental and food matrices, now depend on modern SPE techniques. Additionally, SPE is also popular in drug extraction workflows from biological fluids in forensic labs and the DMPK disciplines.


Commonly, there are four steps involved in an SPE method: conditioning, loading, washing, and eluting. The intent is to simplify complex sample matrices, purify the analytes of interest, fractionate a complex mixture of active compounds, or concentrate any trace levels of analytes. Different strategies and extraction schemes may apply depending on the exact application of the SPE process.


The ionRocket from BioChromato Inc is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionisation and analysis by mass spectrometry.


Direct Analysis in Real Time Mass Spectrometry (DART-MS) is a proven technique that enables rapid analysis of both solid and liquid samples under standard laboratory conditions without sample preparation. However, certain polymers, cosmetic powders and forensic materials are difficult to analyse using DART-MS due to the varying volatility of substituents in these complex samples. Even insoluble samples can be measured using the ionRocket/DART-MS set-up without treatment.


To overcome these challenges, BioChromato developed an innovative sample introduction device (ionRocket), which gradually heats a sample placed directly beneath the DART-MS gas stream. Gradient heating of the sample before ionisation creates time/temperature resolved mass spectra, separating species both by their thermal desorption profiles and mass to charge ratio (m/z).


ionRocket generates a temperature gradient from ambient up to as high as 600ºC in just a few minutes. This allows compounds in your samples to be sublimated, vaporised, or pyrolysed according to their volatility, and then introduced into the DART-MS gas stream. Because the ionRocket offers the option to weigh samples prior to analysis this results in reproducible MS intensity, allowing calibration curves of analyte amount versus peak intensity to be calculated.


Data obtained from ionRocket yields another axis of data (time/ temperature) beyond that obtained from normal DART-MS analysis. Species desorb in order of their volatility along the temperature gradient, and therefore are separated in time. The data produced resembles that of an LC-MS or GC-MS chromatogram, consisting of temperature/time, m/z, and intensity. This can separate rare from abundant species, making them easier to detect.


Watch a video introduction to ionRocket operation: ilmt.co/PL/rWMo More information online: ilmt.co/PL/jz9g


For More Info, email: email:


For More Info, email: email:


54704pr@reply-direct.com Certified Reference Standards


Analytical Standards and Certified Reference Standards Analytical Standards and Certified Reference Standards


If you’ve developed an SPE workflow using manual applications, it’s possible to automate these methods easily using Gilson extraction instruments and systems. You can optimise your process for greater consistency, improve your regulatory compliance, and reduce human error. Developing an automated SPE solution as part of your analytical workflow allows you to run your workflows unattended. You’ll benefit from greater consistency in your liquid handling and sampling purification processes with continuous optimisation and improvement of the entire SPE workflow.


Gilson provides a broad array of automated SPE products to meet the discussed needs. These include the ASPEC® 274 Systems, which are best used with ASPEC®


More information online: ilmt.co/PL/Xj4L and ilmt.co/PL/9Ery For More Info, email:


55294pr@reply-direct.com


Rotational Tapered Bearing Simulator (TBS) viscometer – High Temperature High Shear (HTHS) method of choice


Developed in 1979 by Mr. Ted Selby of Savant Inc., and under multiple patents, the rotational TBS Viscometer became the world’s first commercial high shear viscometer for measuring viscosities of automotive engine oils and fluids under High Temperature, High Shear (HTHS) conditions. Today, the TBS (Tapered Bearing Simulator) remains the modern benchmark ‘referee’ instrument method for HTHS viscometry due to its innovative precision measuring technique, robust design, and notable operational features and is exclusively available through Tannas Co.


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The coaxial tapered Rotor/Stator Set design permits the exact measurement of rotor position and the torque response of the liquid’s resistance to flow (viscous friction), which determines the apparent fluid viscosity. Applying a constant and linear shear rate profile continually to the fluid makes the TBS an absolute viscometer where ‘true’ shear rate is calculated from known dimensions and speed of rotation – no need for shear rate corrections or the possibility of erroneous results due to clogged capillaries.


The TBS Viscometer is associated with several industry test methods; ASTM D4683, D6616, and CEC L-36 for HTHS viscosity at 100°C and 150°C. The D4683 method is included in the SAE J300 Engine Oil Viscosity Classification System and the ILSAC GF series Engine Oil Specifications – the most recent being GF-6, API SP, and CK-4/FA-4 specifications. The CEC L-36 method is utilised for HTHS measurements in the European ACEA engine oil specifications.


The two TBS models available are the long-standing TBS 2100E-F and the newly introduced TBS 3000, depending on your testing needs. The TBS provides viscosity measurements of fresh and used oils over a broad shear rate range and temperature range (40°C to 180°C). The TBS 3000 is a redesigned and re-innovated model providing multiple enhancements to electrical and temperature components, automation, calibrations, and oil injection features, improving the overall user experience.


For more information on the features and benefits of these two TBS models, visit us at TannasKing.com. More information online: ilmt.co/PL/3Wyk


Precise engine intake air with an XCP® integrated Engine Air Control System


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CFR Engines Inc. offers the Engine Air Control System (EACS) for precise management of engine intake air and auxiliary cooling. Users can rely on the factory design and performance of a complete octane test package, when the EACS is paired with a CFR®


recommended exhaust components. The EACS carries the CE Mark and like all CFR products, it is made in the USA.


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Certified Reference Standards


Established in 1962, we pride ourselves in setting the standard for high purity chemicals. Chem Service is accredited to ISO Guide 34:2009, ISO/ IEC 17025:2005, and registered and certified to the ISO 9001:2008 Quality Management System for the design, development, production, distribution, and servicing of organic neat and synthetic reference materials.


• Setting the standard for over 55 years. • Setting the standard for over 55 years.


• More than 14,000 products to choose from and adding new products daily. • Custom Mixtures, Solutions, and Custom Synthesis available.


See us at Pittcon 2019 at Booth 2007


chemservice.com • info@chemservice.com • 1-800-452-9994 chemservice.com | info@chemservice.com | 1-800-452-9994


chemservice.com | info@chemservice.com | 1-800-452-9994 chemservice.com • info@chemservice.com • 1-800-452-9994


• More than 14,000 products to choose from and adding new products daily. • Custom Mixtures, Solutions, and Custom Synthesis available.


Established in 1962, we pride ourselves in setting the standard for high purity chemicals. Chem Service is accredited to ISO 17034, ISO/IEC 17025, and registered and certified to the ISO 9001 Quality Management System for the design, development, production, distribution, and servicing of organic neat and synthetic reference materials.


The EACS easily integrates with existing units to form an overall octane testing system, and leverages XCP Technology to produce the most reliable Octane Number. The Engine Air Control System can be used with any existing engine, including those using a Legacy control panel. However, when the EACS is used on an engine with an XCP panel, the EACS becomes part of the overall system managed by XCP Technology. This integration with XCP allows users to fully manage the EACS from the central HMI of the XCP. It also provides automatic data recording of the EACS performance by the XCP and includes the engine intake air humidity on the final octane test report for improved accountability.


With a nominal design operating range of 60°F – 100°F (16°C – 38°C) and 10-60% relative humidity, the standard production EACS can reliably support operation in nearly all global environments. Additionally, the EACS provides carburetor coolant at a temperature range of 33°F – 50°F (0.6°C – 10°C). Management of engine intake air temperature, precise control of intake air humidity, and proper use of carburetor cooling are all critical to meeting the precision that a documented and defendable Octane Number test requires. Controlling variables and achieving a successful octane test is easier while using an EACS integrated with XCP Technology.


More information online: ilmt.co/PL/kOwm For More Info, email:


WWW.PETRO-ONLINE.COM


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52853pr@reply-direct.com F1/F2 unit and CFR 55867pr@reply-direct.com 271 and ASPEC® SPE Cartridges. These systems have the capability to handle both small and large


sample volumes. This is a key benefit for handling a wide variety of food and beverage matrices along with advanced SPE protocol compliance. These systems provide sample preparation and clean -up of high reproducibility.


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